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This paper investigates the problem of adaptive fault-tolerant control for a class of nonlinear parametric strict-feedback systems with multiple unknown control directions. Multiple sensor faults are first considered such that all real state variables are unavailable. Then, a constructive design method for the problem is set up by exploiting a parameter separation and regrouping technique. To circumvent the main obstacle caused by the coupling effects of multiple unknown control directions and sensor faults, a region-dependent segmentation analysis method is proposed. It is proven that the closed-loop system is globally exponentially stable. Simulation results are presented to illustrate the effectiveness of the proposed scheme.

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