Background: Cadmium is a toxic metal and a known endocrine disruptor capable of altering sex hormone levels especially in the occupationally exposed persons. Some phytochemicals including green tea (Camellia sinensis) may prove to be beneficial in reducing blood cadmium levels and the associated adverse health effects. Aim: This study assessed the levels of blood cadmium and male sex hormones in automobile workers as well as the effect of subsequent green tea supplementation.

The effects of Kerosene, gasoline, and liquefied petroleum gas and biomass fuel exposure on biomarkers of kidney and liver were investigated in male wistar rats. Fifty adult male wistar rats were randomly assigned to five groups of ten animals each. Rats in group A served as control (exposed to fresh air). Group B, C, D and E were exposed to inhalation of kerosene, gasoline, liquefied petroleum gas and biomass fuel (wood smoke) respectively. All the exposures were done using whole body exposure chambers 70 cm x 60 cm x 60 cm measurement for six weeks, 6 days per week. Five millilitres of blood sample were collected and serum extracted at the end of six weeks. The serum concentration of urea, creatinine, uric acid and activities AST, ALT, γGT were determined using Cobas reagent kits manufactured by Roche Diagnostics GmbH, Sandhofer Strasse 116, D-68305 Mannheim, Germany. Values were analysed statistically using SPSS version 23.0.  The result shows significant increase in the serum  levels of urea, creatinine and uric acid of test groups relative to control (p<0.05), though the effect appear to be more pronounced with exposure to kerosene, gasoline and biomass fuel. The exposure also led to significant increase in activities of AST, ALT and γGT (p<0.05). These results suggest that repeated exposure to kerosene, gasoline and liquefied petroleum gas and biomass fumes may elicit hepatic and renal toxicity, thereby impairing the normal liver and kidney function.

Infertility is a common cause of marital disharmony in Nigeria because of the high premium placed on child bearing. Male factor is a significant contributor and declining male fertility rate has been observed over the past decade. Oxidative stress has been implicated in the aetiology of male infertility. The objective of the study was to compare the serum levels of oxidative stress markers (TAC – Total Antioxidant Capacity, MDA - Malondialdehyde and SOD – Superoxide dismutase) in male partners of fertile and infertile couples. This was a case controlled study carried out over a period of 8 months on male partners of infertile couple. Thirty-six were male partners of fertile couple with normal semen parameters and no history of infertility while 73 were male partners of infertile couple which consists of 28 males with oligospermia, 28 with oligoasthenospermia and 17 with asthenospermia.. Serum markers of oxidative stress (TAC, MDA and SOD) were evaluated and compared among the group. The male partners of infertile couple showed significantly low levels of TAC (P = 0.000), SOD (P = 0.000) and significantly high levels of MDA (P = 0.000) when compared with male partners of fertile couple (750.93±146.37 versus 1269.20±330.79, 11.22±3.33 versus 13.96±1.38 and 2.48±1.20 versus 1.51±0.19). Oxidative stress may be a major contributor to male infertility. Its assay may be of importance in prevention and treatment of male infertility.

Background: Obesity is a major public health issue worldwide, contributing to increased cardiovascular diseases, diabetes, insulin resistance and oxidative stress. This is due to sedentary lifestyles; poor dieting and low consumption of antioxidant supplement (example green tea). The objective of this study was to evaluate the level of fasting blood sugar, insulin, insulin resistance blood pressure and MDA in obese subjects and subsequent effect of green tea at 6weeks and 12weeks supplementation. Methods: This was a cross sectional and interventional study. In the cross sectional study, 88 obese subjects (46 class I and 42 class II obese) and 50 normal weight subjects (control) were recruited. In the interventional study, 20 male obese subjects were randomly selected and were given 200ml of commercially prepared green tea. Fasting blood samples were collected before the Original Research Article

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