Schiff base denotes a reaction product of a primary amine and a carbonyl compound. Schiff bases possess a wide variety of biological activity specially antibacterial and antifungal properties. Metal complexes of Schiff base have been studied for their biological activities. This review articles provide a summary of medicinal chemistry features of Schiff base and various reports published on biological activities of Schiff base and its metal complexes.

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201. -The absolute stereochemistry of the new antifungal and antibacterial antibiotic (VI), produced by Streptomyces sp.201, is established by total synthesis. -(BORUWA, J.; KALITA, B.; BARUA*, N. C.; BORAH, J. C.; MAZUMDER, S.; THAKUR, D.; GOGOI, D. K.; BORA, T. C.; Bioorg. Med.