A series of porphyrin-cored glycodendrimers containing 8, 12, 16, and 24 β-D-glucopyranose units at the periphery, have been synthesized by convergent methodology using click chemistry. The structure of developed dendrimers is established by (1)H and (13)C NMR, IR, MALDI-TOF MS, and SEC analysis. Absorption-emission behavior of dendrimers and its modulation under the influence of the dendritic environment is also investigated.
The glycoconjugation of biologically privileged 1,3,4‐oxadiazole scaffold is described via Cu(I)‐catalyzed azide–alkyne cycloaddition. A series of glycosyl alkynes 1b–i, obtained from various commercial sugars, were treated with azide functionalized 1,3,4‐oxadiazole using click chemistry to access triazole‐linked glycosylated 1,3,4‐oxadiazoles 10b–i in good yields. The structure of the developed glycoconjugates has been ascertained by extensive spectroscopic analysis (1H &13C NMR, IR, and MS).
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