Ms. Dorit Gurfel provi ded skillful technical assistance. Dr. T. Wal seth synthesized cADPr and 8-NH,-cADPr and kindly provi ded them for this investigation. Drs. U. Walter and P. De Camilli generously donated antiserum to PKG. Drs. S. Vincent and T. Wal seth provi ded useful comments on an earlier version of this manuscript.
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