The Myrtus nivellei Batt. and Trab. is an endemic shrub of the central Sahara, known for its respiratory anti-infective and hypoglycemic properties. This work consists of a physicochemical, chromatographic and spectral analysis of essential oils extracted from leaves harvested in the region of Tamanrasset in southern Algeria. The extractive yield is 1.6 ± 0.05 (ml/100g of dry plant), the refractive index is 1.4700 ± 0.0005 and the relative density is 0.9052 (g/ml). GC-MS made it possible to inventory thirty-six (36) compounds: 78.55% of monoterpenes, essentially oxygenated, including 1,8-Cineole which represents the majority compound at 33.95%; which could partly explain the anti-infectious properties of Hoggar Myrtle essential oil.

Spirulina or Arthrospira platensis is a filamentous cyanobacterium known for its nutritional properties. The aim of this work is to provide an overview of the consumption and artisanal production of this microalgae in Tamanrasset in southern Algeria. The study demonstrates that there are three determining factors: temperature, light, and pH of the environment. The field survey provided information on the profile of consumers, mode, reason, and frequency of use. It also allowed for the identification of a profile of consumers who believe in the therapeutic virtues of spirulina, although it is only a dietary supplement, making chemical and pharmacological screening more than essential.

The management of beta thalassemia may require periodic blood transfusions, iron chelation therapy, and bone marrow or stem cell transplantation. This study is a descriptive retrospective analysis of clinical, biological, and therapeutic parameters to evaluate the impact and effectiveness of chelation therapy in managing post-transfusional hemochromatosis in 26 β-thalassemia patients treated at the Hussein Dey University Hospital Center in Algiers, Algeria. The results of this study show a certain correlation between the doses of iron chelators taken and the improvement in ferritin levels and creatinine clearance, which is indicative of a reduction in renal function impairment. Five profiles were identified based on this relationship. The study also found that all patients had normal kidney function, but there was a tendency towards a decrease in creatinine clearance, necessitating continuous monitoring. It is important to note that even with careful monitoring, complications of thalassemia may occur gradually and at a late onset. This study highlights the need to integrate pharmaceutical practices and introduce the concept of clinical pharmacy to improve adherence to long-term chelation therapy and ultimately enhance survival in children with major thalassemia.

This work focuses on the phytochemical study and biological activity (antimicrobial) of the aerial parts of the Artemisia campestris collected from the Ahaggar National Park in southern Algeria. After extraction of the essential oil, chromatographic and biological analyzes were carried out on this species. The results show an average essential oil yield of 0.6±0.02 ml per 100 g of dry plant. Chromatographic analysis of the essential oil of Artemisia campestris subsp. glutinosa is rich in monoterpene compounds (50.47%), particularly in hydrogenated forms (40.24% of α and β-pinene) and sesquiterpenes (35.75% of Spathulenol (8.47%), β-Eudesmol (4.67%), and Carvomenthene (3.37% )... The study of antimicrobial activity revealed a remarkable antifungal activity for Candida albicans that could be exploited therapeutically.

The Myrtus nivellei Batt. & Trab. is a shrub native to the Mediterranean and endemic to the central Sahara in the Hoggar massif of southern Algeria, whose leaves are used by the Tuareg, in infusion mixed with tea, against diarrhea, fever, diabetes and for its anti-infective properties. The hypoglycemic activity of the essential oil extracted from the leaves by hydrodistillation. has been demonstrated, with a significant decrease (P<0.001) in blood sugar levels and blood triglyceride levels in diabetic rats after the 2nd hour and up to the 3rd hour of administration (14% and 22%). This drop in blood sugar was not observed in healthy rats treated with the essential oil. The essential oil did not improve the weight of the rats, nor their cholesterolemia. The antimicrobial activity of the essential oil has been studied for six microorganisms. Bacillus subtilis and Candida albicans are the most sensitive, they were inhibited from 2.5/1000 v/v. This oil is also active on Staphylococcus aureus at a concentration of 5/1000 v/v. This activity was weak against Escherichia coli and absent against Pseudomonas aeruginosa and no activity was detected against Enterococcus faecium. It would be interesting to combine these evaluations with chromatographic and spectral studies to determine the compounds responsible for these activities.