Purpose: To determine whether the addition of a low concentration (3.5%) of dextrose would minimize pruritus while maintaining the quality of analgesia.Methods: In a double blind study 48 parturients in early labour were randomized to one of two study groups: dextrose (Dex, n = 24; 10 µg sufentanil in dextrose 3.5%), or normal saline (NS, n = 24; 10 µg sufentanil in normal saline). Parturients received the study drug as the intrathecal injection of the combined spinal-epidural (CSE) technique for labour analgesia. Duration and degree of analgesia were measured until epidural analgesia was initiated or delivery of the baby. The intensity and distribution (above T 6 , T 6 -L 1 , and below L 1 ) of pruritus were measured at five minute intervals during first 25 min after injection.Results: Quality and duration of analgesia did not differ between groups, but the overall incidence of pruritus was less in the Dex group (88% vs 42%, P = 0.001). Within each region, the incidence of pruritus was less in the Dex group. In patients who had pruritus, for the Dex group, the incidence of pruritus in the upper region (>T6) was lower than the NS group. There was no difference in the lower regions.
Conclusion:The addition of dextrose 3.5% to intrathecal sufentanil reduced the incidence of pruritus without affecting the duration or quality of analgesia in parturients in early labour. The distribution of pruritus in the Dex group was limited to below T 6 suggesting that pruritus to intrathecal sufentanil is mediated at the spinal level.Objectif: Vérifier si l'ajout d'une faible concentration (3,5 %) de dextrose réduit le prurit pendant le maintien de l'analgésie.Méthode : Lors d'une étude à double insu, 48 parturientes en début de travail obstétrical ont été réparties en deux groupes : dextrose (Dex, n = 24; 10 µg de sufentanil dans du dextrose à 3,5 %) et soluté physiologique (SP, n = 24; 10 µg de sufentanil dans un soluté physiologique). Elles ont reçu le médicament étudié en injection intrathécale comme composante d'une analgésie rachidienne et péridurale combinée (RPC). La durée et le degré de l'analgésie ont été mesurés jusqu'à ce que l'analgésie péridurale soit commencée ou jusqu'à la naissance du bébé. L'intensité et la distribution (au-dessus de T 6 , T 6 -L 1 , et sous L 1 ) du prurit ont été mesurées à cinq minutes d'intervalle pendant les 25 premières min après l'injection.Résultats : La qualité et la durée de l'analgésie n'ont pas présenté de différence intergroupe, mais l'incidence globale de prurit a été plus faible dans le groupe Dex (88 % vs 42 %, P = 0,001). Pour chaque zone, l'incidence de prurit a été moindre dans le groupe Dex. L'incidence de prurit dans la zone supérieure (> T6) a été plus faible chez les patientes du groupe Dex que chez celles du groupe SP. Le prurit de la zone inférieure ne présentait pas de différence intergroupe.Conclusion : L'addition de dextrose à 3,5 % à du sufentanil intrathécal a réduit l'incidence de prurit sans changer la durée ou la qualité de l'analgésie chez des parturientes en d...
Intracranial subdural hematoma (SDH) formation is an uncommon but serious complication of planned or unintentional dural puncture (DP) during straight epidural anesthesia, combined spinal-epidural, dural puncture epidural, or spinal anesthesia. Diagnosis of intracranial SDH following neuraxial anesthesia may be delayed or misdiagnosed due to rare occurrence, lack of knowledge, as well as an overlap in clinical presentation with postdural puncture headache (PDPH). Increased awareness of intracranial SDH as a complication of DP may result in earlier recognition and prevention of potentially devastating outcomes. This article reviews the relevant literature on association of neuraxial anesthesia with intracranial SDH formation.
Key words: Intracranial subdural hematoma; Anesthesia, Neuraxial; Anesthesia, Epidural; Combined spinal-epidural; Dural puncture; Anesthesia, spinal; Pregnancy; Postdural puncture headache
Citation: Dhoon TQ, Joshi J, Portnoy D, Rajan GC. Intracranial subdural hematoma: a rare but serious complication following neuraxial anesthesia in obstetric anesthesia. Anaesth. pain intensive care 2021;25(6):828-831:
DOI: 10.35975/apic.v25i6.1719
Received: August 4, 2021, Reviewed: September 2, 2021, Accepted: October 3, 2021
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