Objective: Testing the PEST-analysis for assessing of influence of environmental factors on the emotional state of the medical personnel of the Volgograd Region State Budgetary Healthcare Institution "Central District Hospital of the Dubovsky Municipal District" in the context of professional burnout. Results: Determination of the level of professional burnout showed that the hospital's health workers are subject to emotional burnout, which is associated with a busy schedule and high responsibility. The formation of professional burnout (exhaustion) is 20% of the respondents, while 17% have already formed it. The staff's opinion regarding the influence of environmental factors on the emotional state of health workers coincided with experts' opinion, economic and socio-cultural factors were highlighted by them as priorities. The most significant contribution was decreasing the population's real disposable income with an increase in tariffs for paid medical services (81.7%). Among the internal environment factors, the most significant influence on the psycho-emotional state of medical workers, according to the respondents, is exerted by relationships with colleagues within the team (51.7%) and material incentives (70.0%). Conclusion: PEST-analysis allows to supplement the overall picture of assessing medical workers' professional burnout to develop programs to prevent this phenomenon.