Background: Cancer diagnosis and its treatment highly affects negatively on health-related quality of life of children with cancer in physical, social, psychological, and cognitive dimensions in addition to put their care giver in a challenging situation.The aim: of this study was to evaluate the effect of educational training program for mothers about care of their children with cancer and its effect on children health status. Quasi-experimental research design was used in the study, a convenient sample of 50 mothers and their children with cancer at inpatient and outpatient departments at Oncology Institute in Mansoura City for six months from November 2013 to April 2014.The tools: of data collection were an interview questionnaire formto collect data about socio-demographic characteristics for studied mothers and their children, assessment of knowledge& reported practice related childhood cancer and chemotherapy sheet and assessment of children health status scale. The results: revealed that There were statistically significant improvements in mother's knowledge and reported practice with p. value P<0.001.Subsequently, the results lead to a positive impact on their children's health status (physical, psychological, and social status),while there were no statistically significant improvement in children school achievement and their self-care .The study recommended: periodic or continuoustraining program should be applied for mothers and their child in the pediatric oncology departments to improve their knowledge and practice about childhood cancerwhich can increase improving in physical, psychological and social dimensions for children and subsequently improving of school achievement and self-care as possible.

Background: Cancer is a life threatening illness that involves emotional distress, fear of the unknown and changes in life priorities for the child and family. It is at a significant risk of depression for mothers because of the frequent stressful diagnostic tests, treatments and side effects of treatments.Aim: Assessof knowledge and reported practice of mothers having children with cancer and undergoing chemotherapy.Design: Adescriptive research design was used in the study. Data collection: a purposive sample of 50 mothers and their children with cancer at inpatient and outpatient departments at Oncology Institute in Mansoura City. Tools: An interview questionnaire formto collect data about socio-demographic characteristics for studied mothers and their children, assessment of knowledge related childhood cancer and chemotherapy sheet and reported practice of mothers related to care of their children who undergoing chemotherapy sheet. Results: revealed that, only 14% of mothers had satisfactory knowledge related childhood cancer and chemotherapy .In relation to total reported practice, only 34.0% of the studied mothers had total reported practice related to side effects management of chemotherapy.The study recommended: developing frequent educational training programs for mothers of children with cancer about care of their children who undergoing chemotherapy through updated posters, booklets and brochures and a repeat of this research on a large sample and in various places in Egypt for improving mother's knowledge and practice.

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