Vitamin D has a wide range of biological effects. There is evidence suggesting an important role of vitamin D in women's reproductive health, yet there has been no research focusing on newborns in South Russia. The purpose of this current study was to analyze the levels of vitamin D in newborns in the Stavropol Region. The clinical, anamnestic, and laboratory examination involved 60 newborns. The levels of vitamin D were assessed based on serum content of calcidiol, while the mothers' pregnancy courses were also taken into account. The mean content of serum 25(ОН)D 3 was 9.9±0.7 ng/ml. The study showed that the vast majority of the patients (98.3%) lacked vitamin D while in over a half of them (56.7%) the deficiency was severe. It was shown that complicated somatic, obstetric and gynecological history is an important factor for antenatal hypovitaminosis D in newborns (р<0.05). In case of mothers' taking multivitamin preparations through pregnancies, severe vitamin D deficiency in newborns had an occurrence twice below that in infants whose mothers failed to take additional vitamin supply (р<0.001). There is confirmation to the need for targeted antenatal prevention of hypovitaminosis D in order to reach proper levels of calciferol in the early neonatal period. Key words: vitamin D, newborn, hypovitaminosis d, pregnancy failure, antenatal prophylaxisВитамин D оказывает широкий спектр биологических эффектов. Имеются данные, указываю-щие на значимую роль витамина D в репродуктивном здоровье женщин, но до настоящего времени показатели у новорожденных юга России не изучались. Целью исследования был анализ обеспе-ченности витамином D новорождённых детей Ставропольского края. Проведено клинико-анамне-стическое и лабораторное обследование 60 новорождённых. Обеспеченность витамином D оце-нивалась по содержанию кальцидиола в сыворотке крови, из анамнестических данных подробно анализировалось течение беременности у матери. Среднее содержание 25(ОН)D 3 сыворотки со-ставляло 9,9±0,7 нг/мл. Установлено, что у подавляющего большинства пациентов (98,3%) имеет место недостаточное содержание витамина D, более половины (56,7%) страдают тяжёлым дефи-цитом. Показано, что осложнённый соматический и акушерско-гинекологический анамнез являет-about authors:Karpov Sergey Mikhailovich, MD, Professor, head of Department of neurology, neurosurgery, medical genetics,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.