The prescription of resistance exercise often involves administering a set number of repetitions to be completed at a given relative load. While this accounts for individual differences in strength, it neglects to account for differences in local muscle endurance and may result in varied responses across individuals. One way of potentially creating a more homogenous stimulus across individuals involves performing resistance exercise to volitional failure, but this has not been tested and was the purpose of the present study. Individuals completed 2 testing sessions to compare repetitions, ratings of perceived exertion (RPE), muscle swelling and fatigue responses to arbitrary repetition (SET) vs. failure (FAIL) protocols using either 60% or 30% one-repetition maximum. Statistical analyses assessed differences in the variability between protocols. Forty-six individuals (25 females and 21 males) completed the study. There was more variability in the number of repetitions completed during FAIL when compared to SET protocols. Performing the 60% 1RM condition to failure appeared to reduce the variability in muscle swelling (average variance: 60%-SET = .034, 60%-FAIL = .023) and RPE (average variance: 60%-SET = 4.0, 60%-FAIL = 2.5), but did not alter the variability in muscle fatigue. No differences in variability were present between the SET-30% and FAIL-30% protocols for any of the dependent variables. Performing resistance exercise to failure may result in a more homogenous stimulus across individuals, particularly when using moderate to high exercise loads. The prescription of resistance exercise should account for individual differences in local muscle endurance to ensure a similarly effective stimulus across individuals. Highlights. There is a large variance in the number of repetitions individuals can complete even when exercising with the same relative load. . Ratings of perceived exertion and muscle swelling responses become more homogenous when exercising to volitional failure as compared to using performing a set number of repetitions, particularly when moderate to higher loads are used. . The prescription of exercise should take into consideration the individual's local muscle endurance as opposed to choosing an arbitrary number of repetitions to be completed at a given relative load.

Introduction An appropriate comparison of different cuff widths during blood flow restricted exercise requires that the cuffs are inflated to the same relative pressures. Narrow cuffs tend to be preferred and may reduce discomfort when applied during resistance exercise, but whether this is also true during walking exercise remains unknown. Methods Individuals completed two identical walking trials, once with 12‐cm wide cuffs and once with 17‐cm wide cuffs. Five 2‐min walking bouts were completed at a speed of 50 m/min, with a 1‐min rest period between sets. The restriction cuffs were inflated to 40% of the individuals’ arterial occlusion pressure taken with each respective cuff. Individuals were asked to rate their discomfort, perceived exertion (RPE), and cuff preference. Results Twenty‐seven individuals completed the study. The 12‐cm cuff required a higher occlusion pressure which resulted in a higher absolute pressure applied (58 vs. 52 mm Hg; BF10 = 19 331.897). Whilst there was no difference in RPE values between cuffs (BF10 = 0.474), individuals reported greater discomfort when using the wider cuffs (2.3 vs. 1.7; BF10 = 252.786). The majority of individuals (63%) preferred to use the narrower cuff, whereas fewer preferred the wider cuff (26%) and even fewer did not have a preference (11%). Discussion Blood flow restricted walking exercise performed with narrower restriction cuffs appeared to reduce participant discomfort whilst also being preferred over that of wider cuffs. Future studies may wish to test the influence of different restrictive cuff widths on alterations in gait patterns during blood flow restricted walking exercise.

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