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Linezolid (LZD) was the first oxazolidinone approved for treating drug-resistant tuberculosis. A newly approved regimen combining LZD with bedaquiline (BDQ) and pretomanid (PMD) (BPaL regimen) is the first 6-month oral regimen that is effective against multidrug- and extensively drug-resistant tuberculosis.

Soft robots present an avenue toward unprecedented societal acceptance, utility in populated environments, and direct interaction with humans. However, the compliance that makes them attractive also makes soft robots difficult to control. We present two low-cost approaches to control the motion of soft actuators in applications common in human-interaction tasks. First, we present a passive impedance approach, which employs restriction to pneumatic channels to regulate the inflation/deflation rate of a pneumatic actuator and eliminate the overshoot/oscillation seen in many underdamped silicone-based soft actuators. Second, we present a visual servoing feedback control approach. We present an elastomeric pneumatic finger as an example system on which both methods are evaluated and compared to an uncontrolled underdamped actuator. We perturb the actuator and demonstrate its ability to increase distal curvature around the obstacle and maintain the desired end position. In this approach, we use the continuum deformation characteristic of soft actuators as an advantage for control rather than a problem to be minimized. With their low cost and complexity, these techniques present great opportunity for soft robots to improve human–robot interaction.

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