More than 80% of the population in Africa by the World Health Organization (WHO) leans on endogenous knowledge to solve their primary health care problems. In this study, we examined the relevance of Costus afer Ker Gawl, a plant called ginger lily, spiral ginger or bush cane. It is believed to be used in traditional medicine practice (TMP) to treat and manage many conditions including diabetes mellitus, stomach ailments, arthritis, inflammation. These alleged traditional incited large researchers to conduct studies on the plant to amass scientific evidence. However, these results are sparse, and thus, an inventory through the present search using online search engines such as Google Scholar, PubMed, Science Direct, Web of Science, Scopus and Chemical Abstracts for the period from 1990 to 2021; provides a bibliographic actualization on the plant, taking into account its traditional uses, phytochemical and nutritional constituents, pharmacological activities and toxicological effects. The online search included the use of the keywords, "Costus afer Ker-Gawl" or "Costus afer". It should be noted that the stem and leaves of the plant contain consistent amounts of micronutrients and macronutrients. The leaves, stem, rhizomes of C. afer contain several steroidal sapogenins, aferosides, dioscin and paryphyllin C and a flavonoid glycoside, kaempferol-3-O- \(\alpha\)-L-rhamnopyranoside. Experimental studies on various parts of the plant have shown biological activities such as anti-hyperglycemic, hepatocellular protection, cardioprotection, nephroprotection, CNS depressant, analgesic, antiarthritis, antibacterial and antioxidant. This wide range of biological properties of Costus afer Ker Gawl would be largely attributed to the essential oil compounds such as Sabinene, \(\beta\) -pinene and \(\beta\) -caryophyllene which are among the major compounds of this plant. Based on these obvious data, it is concluded that the plant could be used as an alternative and complementary therapy for many diseases related to oxidative stress so will guide us future research on the use of Costus afer Ker Gawl as an anti-inflammatory.

Aims: Promote Annona muricata (Graviola) and provide information on its phytochemistry and bioactivity. Study Design: Multidisciplinary advanced bibliographic surveys, utilization of ChemBioDraw software package, and dissemination of the resulted knowledge. Place and Duration of Study: UR73, Development in Pedagogy and Health, Interdisciplinary Research Center of the National Pedagogical University, National Pedagogical University, Kinshasa, the Democratic Republic of the Congo, between June 2021 and July 2022. Methodology: A bibliographic review was carried out to acquire information on the pharmacognosy and phytochemistry of A. muricata from various electronic databases (PubMed, PubMed Central, Science Direct and Google Scholar). The terms phytochemistry, pharmacognosy and the scientific name of this plant species were used as keywords for the search. The ChemBioDraw Ultra 15.0 software package was used to draw the chemical structures of natural compounds of A. muricata. Results: From the results obtained, it should be noted that A. muricata is traditionally used as an analgesic or stimulant. Various studies inform that this plant has various pharmacological properties such as anti-inflammatory, antimicrobial, antihyperglycemic, antioxidant, antihelminthic, cytotoxic, antipyretic, analgesic, healing and anti-sickling effects. Many natural phytochemicals like tannins, alkaloids, phenols, glycosides, flavonoids and steroids are responsible for its properties. Conclusion: This review therefore helps to inform future research on the design and development of new relevant drugs from A. muricata to improve human health and well-being. Especially drug candidates for the treatment of cancer and tuberculosis.