Purpose: We assess the prevalence of overactive bladder (OAB) and its risk factors in a male urologic veterans population. Materials and Methods: Validated self-administered questionnaire was prospectively given. Results: Among 1086 patients, OAB was present in 75%, of which 48% had not been diagnosed/treated. The risk of OAB increased with age. OAB was not associated with BMI, smoking, race, diabetes, CHF, and COPD. Conclusions: The prevalence of OAB in this population is under-diagnosed and under-treated.

First-trimester screening for fetal aneuploidy using nuchal translucency (NT), pregnancy-associated plasma protein A, free or total beta-hCG, and maternal age constitutes a very effective screening test for fetal Down syndrome. We describe a case in which a patient presented at 14 weeks' gestation with an acute abdomen 1 week after first-trimester screening (including NT measurement) performed elsewhere, which was negative for trisomies 21 and 18. Sonographic examination revealed an interstitial pregnancy with a singleton fetus with present cardiac activity, which had not been noted 1 week earlier at the time of earlier transabdominal NT measurement. This case indicates that successful acquisition of a NT measurement during first-trimester screening for fetal aneuploidy does not negate the rare possibility of an unusual ectopic pregnancy.

No abstract

To study the prevalence and risk factors of the overactive bladder, urinary incontinence and other lower tract urinary symptoms in patients with uterine myomas, female patients with established diagnosis of the uterine myomas presenting to gynecology clinic were invited to answer a self-administered questionnaire, which included questions on evidence of lower urinary tract symptoms [modified Overactive Bladder-Validated 8-question Screener (OAB-V8)]. Demographic data, relevant medical and surgical history, and pelvic ultrasound findings were reviewed from the patients charts. Statistical significance of relationship between OAB, stress incontinence and urge incontinence in relation to body mass index (BMI), uterine volume and size of dominant myoma were analyzed using 2-taild exact Fisher test and Wilcoxon test. Ninty-eight patients (28 to 81 years) completed the questionnaire over a period of 3 months. The majority were premenopausal and had detectable myomas on ultrasound. OAB was present in 47.9% women. No significant statistical relation between size and volume of the uterus and overactive bladder, urge incontinence, stress incontinence and mixed incontinence was noted. Observation of OAB subtypes with urge and stress incontinence in premenopausal patients with uterine myomas was statistically significant in comparison with premenopausal women studied (60.8% vs 15.3 and 63% vs 6.8, respectively; P<0.001). Overall prevalence of OAB was similar in both groups. Our study showed the higher prevalence of overactive bladder than in the general population, however overall OAB prevalence related to fibroids did not show statistical significance. OAB-stress incontinence and OABurge incontinence subtypes were associated with uterine myomas