clinicaltrials.gov Identifier: NCT00225641.

trial are effective in their own right. A further incentive for involvement in the trial is the concept of thèone-stop' (or`twoor`two-stop' in the case of our research clinic) menstrual disorders clinic. This type of clinic had not previously been established in our hospital and women otherwise have their menorrhagia managed routinely in a general gynaecology clinic. On completion of the trial, the dedicated menstrual disorders clinic will continue as a routine clinical service. To answer the question asked by the SMART study trialists-ªshould we disregard evidence based medicine and prescribe such therapies without proof?º No, but we may need to be patient in the arrival at such proof, which could involve meta-analysis of rando-mised trials as SMART and TALIS. References 1. Rogerson L, Duffy S, Crocombe W, Stead M, Dawood D. Management of menorrhagia-SMART study (Satisfaction with Mirena and Ablation: a Randomised Trail)[Correspondence]. Br J Obstet Gynaecol 2000;107:1325±1326. 2. Cooper KG, Parkin DE, Garratt AM, Grant AM. Two-year follow up of women randomised to medical management or transervical resection of the endometrium for heavy menstrual loss: clinical and quality of life outcomes. Br J Obstet Gynaecol 1999;106:1231±1232. 3. Lethaby AE, Cooke I, Rees M. Progesterone/progestogen releasing intrauterine systems versus either placebo or any other medication for heavy menstrual bleeding (Cochrane Review). In: The Cochrane Library, Issue 4. Oxford

The Vscan displays image quality interchangeable with larger and more expensive systems. The apparatus is well suited for performing a FATE examination in a 1-day surgery setting and could very well also be applicable in almost any situation involving patients with acute illness.

RFA is an effective method to treat liver metastases from colorectal carcinoma. Survival is improved and comparable with survival following surgical resection. The rate of complications is low.

• Patients eligible for local treatment of colorectal liver-metastases require optimal imaging. • In 80 consecutive patients, MRI had superior per lesion diagnostic performance. • Findings were independent of prior treatment and type of planned local treatment. • Equally, MRI had superior diagnostic performance on per segment basis.