Abstract

This tertiary care hospital based prospective study was performed to compare the effect of single dose prophylactic versus conventional antibiotic therapy in clean surgical cases operated in SSIMS&RC, Davangere. A total of 100 cases were studied, male patients were more compared to females with ratio of 3:2, with mean age of 42.7 years, all clean surgical cases were operated, with highest being inguinal hernia 31%. In this study 6% of cases in group-II and 2% case in group-I had postoperative infection, with most common organism isolated being staphylococcus aureus. This study highlights the judicious use of prophylactic antibiotics in order to prevent emergence of antibiotic resistance and to reduce prolonged hospital stay and cost incurred due to antibiotics.