Odontogenic fibromyxoma in the jaws is infrequent, slow growing, benign, locally aggressive tumor of ectomesenchymal origin with or without odontogenic epithelium and accounting for only 3%-6% of odontogenic tumours. Due to its variable clinico-radiographic characteristics and propensity for recurrence, correct diagnosis is required for adequate management. We present a rare case of odontogenic fibromyxoma occurring in the mandible of a 58-year-old female patient with a brief review of clinical radiological and histopathological features. We also emphasize the usefulness of Cone Beam Computed Tomography in the diagnosis of such lesions. Along with histopathology, cone-beam computed tomography (CBCT) may prove extremely useful in clarifying the intraosseous extent of the tumor and its effects on surrounding structures.