Background: Blood Transfusion Services (BTS) are the vital part of modern health care system without which efficient medical care is impossible. To make blood donation safe and increase the confidence of the masses in voluntary blood donation, many safety measures are implemented by the blood transfusion community. The most important of all safety measures is donor selection. Stringent, meticulous and serious donor screening is necessary to afford protection to blood donors and recipients. Aim & Objectives: The aim of this study was to document the current rate and reasons for donor deferral in our tertiary care Centre. Materials and Methods: This retrospective record based study was carried out for whole blood donors at Dr. B R Ambedkar Medical College Hospital Blood bank. Results: In our study the majority of the registered donors were replacement donors (92.2%). Total 2556 people registered for donating blood during the study period (5 years), of whom 2140 (83.7%) were males. 176 donors were deferred by medical officer based on detailed medical history and brief physical examination of donors with regard to hemoglobin (Anaemia), blood pressure (hypertension), temperature (hyperthermia/fever), and pulse irregularity and rate. The majority of donors were deferred for temporary reasons (61.3%) and others were permanently deferred. Conclusion: The donor deferral rates and reasons for deferral for blood donation are important issues to be highlighted among blood donors, general public, in the blood banks and hospitals. We can add a significant number of donors by recruiting back a large number of temporarily deferred donors by remotivating them after addressing the reason for deferral.

Background: Gestational trophoblastic diseases(GTDs) consists of pregnancy related disorders ranging from benign Hydatidiform mole, Invasive mole to neoplastic conditions including Choriocarcinoma, Placental site trophoblastic tumor and Epitheloid trophoblastic tumor with varying potential for local invasion and metastasis. GTDs mimic growth pattern encountered in early normal placental development, nonmolar abortions and variety of nontrophoblastic lesions. Therefore an appreciation of different types of GTDs with its histomorphological manifestations are important for the confirmation of diagnosis. Thus the study was undertaken. Materials & Methods:The material for the study comprised of products of conception specimens received in the Department of Pathology, J.J.M. Medical college, Davangere, India during the period of 2 years. Detailed gross examination was done before fixation and subsequent microscopic analysis was done.Results: 65 cases of GTDs were diagnosed in 495 cases of products of conception. 37 cases of complete mole, 27 cases of partial mole and one case of Invasive mole were diagnosed. Diffuse hydropic swelling of the villi, round smooth villous outline, circumferential trophoblastic proliferation and focal hydropic swelling of the villi, irregular scalloping outline of the enlarged villi, focal trophoblastic cell proliferation were characteristic features of complete & partial mole respectively. Histomorphological features were analysed in all the cases and compared with studies done by others. Conclusion:The classification and histomorphological analysis of GTDs are important elements for better understanding of the disease. Studies are needed to look for ancillary markers in distinguishing different types of GTDs and for predicting the prognosis.