To realize long-distance quantum communication and quantum network, it is required to have multiplexed quantum memory with many memory cells. Each memory cell needs to be individually addressable and independently accessible. Here we report an experiment that realizes a multiplexed DLCZ-type quantum memory with 225 individually accessible memory cells in a macroscopic atomic ensemble. As a key element for quantum repeaters, we demonstrate that entanglement with flying optical qubits can be stored into any neighboring memory cells and read out after a programmable time with high fidelity. Experimental realization of a multiplexed quantum memory with many individually accessible memory cells and programmable control of its addressing and readout makes an important step for its application in quantum information technology.

We propose an experimentally feasible scheme to generate the Greenberger-Horne-Zeilinger-type of maximal entanglement between many atomic ensembles based on laser manipulation and single-photon detection. The scheme, with inherent fault tolerance to the dominant noise and efficient scaling of the efficiency with the number of ensembles, allows one to maximally entangle many atomic ensembles within the reach of current technology. Such a maximum entanglement of many ensembles has wide applications in the demonstration of quantum nonlocality, high-precision spectroscopy, and quantum information processing.