Prolapse is a common ailment associated with parturition in cattle and buffaloes. An eight-year-old, non-descript buffalo with the history of aggressive assistance during parturition was presented at farmers doorstep for third degree complete uterine prolapse. The prolapsed mass haemorrhagic and soiled, the mass was cleaned maintaining all aseptic measures. Animal was restrained and using the three-step management reduction, reposition and retention of the prolapsed mass was undertaken. The blood parameters indicated anaemia, neutrophilia, and eosinophilia, while the serum profile indicated hypocalcaemia. The case was managed rationally by rehydration, supplementation of energy and calcium. The infection and trauma of uterus was managed with antibiotic therapy, analgesics and antiallergics. The animal recovered uneventfully without a relapse of the uterine prolapse.