ANTECEDENTES: como parte de la etiología de la alergia respiratoria está la genética, los factores prenatales y la sensibilidad a diversos aeroalérgenos, entre estos los hongos. Existe relación entre la sensibilización a hongos en pruebas cutáneas, la patogénesis y el agravamiento de la alergia. En México hay poca bibliografía en relación a la sensibilización a hongos y en el norte del país no existen datos publicados a este respecto.OBJETIVO: evaluar la prevalencia de sensibilización a hongos en pacientes con alergia respiratoria y pruebas cutáneas para aeroalérgenos; determinar el hongo más prevalente, la prevalencia de sensibilización a cada especie de hongo por año y evaluar la prevalencia de sensibilización a hongos por edades.MATERIAL Y MÉTODO: estudio transversal, observacional y descriptivo efectuado del 1 de enero de 2010 al 31 de diciembre de 2014 en pacientes atendidos en el Centro Regional de Alergia e Inmunología Clínica (Monterrey, NL, México). Se revisó una base de datos de pacientes a quienes se realizaron pruebas cutáneas, se valoró la sensibilización a seis especies de hongos. Se realizaron tablas de captura de datos y análisis estadístico.RESULTADOS: la prevalencia de sensibilización a hongos en 4880 pruebas cutáneas practicadas a igual número de pacientes con alergia respiratoria es de 17.1%. La especie de hongo más prevalente fue Alternaria alternata con 5.5%. El límite de edad con mayor prevalencia a sensibilización fue el de 0-10 años con 6.7%.CONCLUSIÓN: la prevalencia de sensibilización a hongos fue mayor que la prevalencia mundial reportada, pero menor que la encontrada en los demás estudios efectuados en México.
Sensitization to fungi is recognized as a risk factor for exacerbations among patients with asthma diagnosis, however, its contribution as a cause of allergic disease is still a subject of debate. The aim of this study is to know the fungal sensitization among patients consulted for respiratory symptoms in a tertiary center of allergy, as well to assess the prevalence by diagnosis, type of fungi and age group. METHODS: A retrospective study was conducted, obtaining data from the records of skin tests of patients attended at an allergy center in
Background: The presence of allergic mucin in allergic fungal sinusitis (AFS) is a manifestation that identifies it as a hypersensitivity process. AFS has a phenomenon of cross-reactivity to IgEbound proteins having at least two shared epitopes. Case report: A 13-year-old male with nasal obstructive symptoms of three years of evolution. An obstructive mass was identified in the sinuses through physical examination and CT. In endoscopic surgery, the left nostril polyp was identified with the macroscopic appearance of allergic mucin; the polyp was resected. Final histopathological examination using periodic acid-Schiff and Grocott's methenamine silver staining indicated Aspergillus. Two weeks after surgery, percutaneous tests showed sensitization to Alternaria, Helminthosporium sativum, and Deramatophagoides farianae with negativity to Aspergillus fumigatus. Conclusions: The absence of significant titers of specific IgE antibodies to Aspergillus fumigatus was the evidence that the hypersensitivity response was triggered by a pathogen other than that isolated in histopathological study, which coupled with positive tests for other fungi may be explained by the cross-reactivity phenomenon in a phenomenon of likely hypersensitivity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.