Background: Breast cancer is one of the most common cancers and a major cause of death in women worldwide. Chemotherapy is mainly used to treat and control the progression of breast cancer. Leukopenia is the most common side effect of chemotherapy which may decrease immune function and further lead to serious fatal infections. The purpose of this study was to evaluate the effect of acupuncture on regulating hematopoietic function in chemotherapy-induced leukopenia among patients with breast cancer. Methods: PubMed, Embase, Cochrane Library, CINAHL Plus, Web of Science, and Chinese articles in the Airiti Library and China National Knowledge Infrastructure (CNKI) databases were searched to August 2021 for papers to include in a systematic review and meta-analysis. A random-effects model was applied. The effect size was calculated by Hedges’ g. Heterogeneity was determined using Cochran’s Q test. Moderator analyses were performed to examine potential sources of heterogeneity. A trial sequential analysis (TSA) was conducted to determine whether the current sample size was sufficient. Results: Ten randomized controlled trials involving 650 participants were eligible for inclusion. Analysis by the random-effects model showed a significant effect by acupuncture of ameliorating leukopenia during chemotherapy. Levels of white blood cells (WBCs) were increased (Hedges’ g = 0.70, P < .001, I2 = 34%), neutrophil counts (Hedges’ g = 0.80, P < .001, I2 = 0%) were significantly enhanced. Moreover, regardless of the manner through which acupuncture was applied, overall values of WBCs increased. Conclusions: The current meta-analysis supports acupuncture possibly ameliorating chemotherapy-induced leukopenia, as WBC and neutrophil values significantly increased after acupuncture in patients undergoing chemotherapy. Additionally, regardless of the type of acupuncture, values of WBCs increased. These findings are actionable and support both the clinical use of acupuncture to relieve chemotherapy-induced leukopenia and further research regarding the use of acupuncture in patients experiencing immunosuppression when undergoing chemotherapy. Trial Registration: PROSPERO-CRD42020215759.

To assess the differences in blood pressure self-management behavior between healthy people and patients with hypertension, and to suggest possible predictors of blood pressure self-management in Vietnam. Methods: A cross-sectional study design was conducted, in a sample of 362 patients with hypertension and 174 healthy people were recruited, using a questionnaire survey. Results: The scores of blood pressure self-management behavior were significantly higher among patients with hypertension compared to healthy people. The living area in rural (β =-2.32, P < 0.0001) and with more than six years duration of hypertension (β = 1.88, P<0.0001) were the predictors for the score of self-management behavior among patients with hypertension, while in healthy people, the score was significantly predicted by higher knowledge of hypertension (β = 0.35, P<0.0001) and education on prevention of hypertension (β = 0.86, P = 0.002). The major source for both patients with hypertension and healthy individuals to acquire health-or hypertension-related knowledge was television or radio program. Conclusion: Patients with hypertension presented with higher scores of self-management behavior. The Vietnamese government should provide more health education program in general population. The development of an credible media technology (e.g., television, radio, internet) is a recommendable stratrgy in disseminating information on the prevention and controlling of hypertension.