Colon cancer arises due to the conversion of precancerous polyps (benign) found in the inner lining of the colon. Prevention is better than cure, and this is very true with respect to colon cancer. Various epidemiologic studies have linked colorectal cancer with food intake. Apple and berry juices are widely consumed among various ethnicities because of their nutritious values. In this review article, chemopreventive effects of these fruit juices against colon cancer are discussed. Studies dealing with bioavailability, in vitro and in vivo effects of apple and berry juices are emphasized in this article. A thorough literature survey indicated that various phenolic phytochemicals present in these fruit juices have the innate potential to inhibit colon cancer cell lines. This review proposes the need for more preclinical evidence for the effects of fruit juices against different colon cancer cells, and also strives to facilitate clinical studies using these juices in humans in large trials. The conclusion of the review is that these apple and berry juices will be possible candidates in the campaign against colon cancer.

We propose a new Hole-filling algorithm by improving the Olympic operator, and we also apply it to generate the volume in our freehand 3D ultrasound reconstruction of the spine. First, the ultrasound frames and position information are compounded into a 3D volume using the Bin-filling method. Then, the Hole-filling method is used to repair gaps in the volume. The conventional Olympic operator defines the empty voxels by sorting the neighboring voxels, removing the n% of the upper and lower values, and averaging them to attain the value to fill the empty voxels. The empty voxel estimation can be improved by thresholding the range width of its neighboring voxels and adjusting it to the average values. The method is tested on a holemanipulated volume derived from a cropped 3D ultrasound volume of a part of the spine. Our MAE calculation on the proposed technique shows improved result compared to all tested existing methods.

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Over recent years, the reseach in the field of soft actuation has been extensively increased for achieving more complex motion path with smooth, high flexible movement and high generated force at minimum operating pressure. This paper presents the study on gripping force capability of soft actuators applied on glove-type finger exoskeleton, developed in motivation to assist individuals having weak finger gripping ability in their rehabilitation exercise towards hand function restoration. The exoskeleton utilizes five cylindrical shaped pneumatic bending actuators developed in the lab, which use fiber reinforcement as a cause of bending motion that drive finger’s flexion movement. Four right-handed healthy volunteers simulated paralysis participated in the study. At 200kPa safe operating pressure, the soft exoskeleton worn by the subjects demonstrates the ability to provide adequate grip force. The grip force generated from exoskeleton worn on passive right hand is 4.66 ± 0.2 N and 3.61± 0.2 N from passive left hand, both higher than the minimum grip forces measured to hold the Hand Dynamometer of 240 g. It shows good potential to be used as a finger rehabilitation assist device.