A 2-year-old female bearded dragon (Pogona vitticeps) presented to the clinic exhibiting lameness and significant swellings bilaterally in the carpal region. On physical examination the lizard was determined to be in obese body condition and pododermatitis was observed on the palmar aspects of both carpi. The rest of the examination was unremarkable. Radiographs revealed opacities present in both carpal joints with possible fluid accumulation. Biochemistry revealed hypercalcemia and hyperphosphatemia. A joint aspirate was performed and submitted for cytology and culture. The sample was sterile and only inflammatory cells were seen. Despite these results, the swelling initially improved with daily lincomycin 5 mg/kg IM but recurred after one month, and the lizard was referred to a specialist center for further investigations. A tissue biopsy was performed and submitted for histology and culture. Histopathologic examination revealed periarticular soft tissue ectopic bone characterized by a proliferation of ectopic cartilage and both lamellar and woven bone with haematopoietically active bone marrow within a fibrous connective tissue stroma. Bacterial culture revealed a scant growth of Staphylococcus aureus and Serratia marcescens. The lizard received ceftazidime 20 mg/kg every 72 hours IM for three weeks. Clinical signs resolved until eight months later when the swellings returned.
Background: Global hypoxic-ischemic brain injury (GHIBI) results in variable degrees of neurological dysfunction. Limited data exists to guide prognostication on likelihood of functional recovery.Hypothesis: Prolonged duration of hypoxic-ischemic insult and absence of neurological improvement in the first 72 hours are negative prognostic indicators.Animals: Ten clinical cases with GHIBI.Methods: Retrospective case series describing 8 dogs and 2 cats with GHIBI, including clinical signs, treatment, and outcome.Results: Six dogs and 2 cats experienced cardiopulmonary arrest or anesthetic complication in a veterinary hospital and were promptly resuscitated. Seven showed progressive neurological improvement within 72 hours of the hypoxic-ischemic insult.Four fully recovered and 3 had residual neurological deficits. One dog presented comatose after resuscitation at the primary care practice. Magnetic resonance imaging confirmed diffuse cerebral cortical swelling and severe brainstem compression and the dog was euthanized.Two dogs suffered out-of-hospital cardiopulmonary arrest, secondary to a road traffic accident in 1 and laryngeal obstruction in the other. The first dog was euthanized after MRI that identified diffuse cerebral cortical swelling with severe brainstem compression. In the other dog, spontaneous circulation was recovered after 22 minutes of cardiopulmonary resuscitation. However, the dog remained blind, disorientated, and ambulatory tetraparetic with vestibular ataxia and was euthanized 58 days after presentation. Histopathological examination of the brain confirmed severe diffuse cerebral and cerebellar cortical necrosis.Conclusions and Clinical Importance: Duration of hypoxic-ischemic insult, diffuse brainstem involvement, MRI features, and rate of neurological recovery could provide indications of the likelihood of functional recovery after GHIBI.
An 11-year-old, male, neutered raw fed greyhound was presented for a 2-week history of progressive non-lateralised, non-painful ambulatory paraparesis, deteriorating acutely to non-ambulatory tetraparesis. Magnetic resonance imaging, cerebrospinal fluid analysis and polymerase chain reaction tests confirmed the diagnosis of meningoencephalomyelitis secondary to Neospora caninum infection. Despite treatment, the patient deteriorated and was euthanased. Postmortem examination revealed diffuse areas of necrotising encephalomyelitis, multifocal non-suppurative encephalomyelitis and areas of necrotising non-suppurative cerebellitis. N. caninum parasitic cysts could also be identified. This is the first case report of correlated histological features and magnetic resonance imaging of meningoencephalomyelitis secondary to N. caninum. This case report was presented as an online poster presentation at the online 33rd ESVN-ECVN symposium.
An 11‐year‐old male neutered British Shorthair cat presented with acute collapse, dyspnoea and paraparesis. Left atrial enlargement and left‐sided congestive heart failure were excluded by point‐of‐care ultrasonography, and gall bladder wall oedema was detected. Comparative venous blood gas analyses confirmed ischaemia of the hindlimbs, and echocardiography was consistent with pulmonary hypertension. The patient was euthanased and a postmortem examination revealed pulmonary artery thromboses associated with bronchioloalveolar carcinoma.
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