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The paper presents the basic characteristics and prerequisites for improving the production of butter lettuce "Shangore" in order to obtain guidelines in the application of lettuce cultivation technology, stable yield, increased nutritional value and uniform quality. Fertilization treatments in the experiment included: phosphate-based mineral fertilizer, humic acid-based organic fertilizer, and liquid organic-mineral fertilizer. The results of this research indicate that the average value of lettuce yield was the highest in the application of fertilizers with potassium phosphate and the application of mulch combination PE - black foil and agrotextiles and amounted to 45,997 kg / ha in 2021. The lowest yield of lettuce was registered in the control variant and amounted to 22,487 kg / ha in 2020.