Results of the research of social and psychological adaptation of students of educational institution with the round-the-clock stay of Orenburg are given in article. It is shown that under the influence of a complex of adverse factors of the intra-school environment the level of social and psychological adaptation of students decreases that is shown by increase in the course of training of number of children with disadaptation in communicative and educational spheres, and characterized by emotional trouble, high level of uneasiness in usual life and in educational activity.

Today education is being modernized in the RF and it involves active development of innovative educational establishments, particularly, those where students stay round-the-clock. Intra-school environment in such establishments has its peculiarities and there are several factors in the educational process there which influence a child's body thus deteriorating his or her physical and mental health. To make educational processes efficient in such establishments, it is necessary to pay close attention to children's neuro-psychic state and quality of their life. Our research goal was to assess students' neuro-psychic state and quality of their life in an educational establishment where they stayed round-the-clock. We performed this assessment via questioning with standard questionnaires. As a result, we revealed that such adverse factors in the intra-school environment as non-rational organization of the educational process and daily regimen led to poorer neuro-psychic state and lower quality of children's life. It became obvious through an increase in number of students with higher anxiety level, from 16 % in the fifth grade to 19 % in the tenth grade. Both physical and mental components of life quality also deteriorated. We revealed that anxiety level and life quality parameters depended on non-rational organization of the educational process and daily regimen. The existing situation calls for working out and implementation of modern preventive healthpreserving activities and active medical support provided for the educational process; these activities should be aimed at lowering risks caused by negative influence exerted by intra-school environment factors on students' neuro-psychic state and quality of their life.