Precast concrete industrial buildings have been widely spreading over the Italian territory mostly devoted to industrial development after WWII. The pioneering structures built in the early decades of this period have been designed with criteria which are now obsolete and with lower static actions with respect to the actual standards, moreover disregarding any conception of seismic or fire resistance. As such, they are a potential source of strong vulnerability. With reference to a large industrial complex located in Brianza (Northern Italy) built with successive expansions from the '40s to the '70s, the structural performance indexes associated to static, seismic and fire loads are evaluated for the different classical typologies of that period, including roofs with truss strut-tie systems, restrained arches, and tapered beams. The costs associated to strengthening/retrofitting are also estimated for each typology.