Purpose To report the frequency and spectrum of conjuctival tumors in an Ocular Oncology Unit from 1992 to 2008. Methods Retrospective noninterventional case series. Review of clinical charts of patients with the diagnosis of conjunctival tumor diagnosed at the Ocular Oncology Unit of the University Hospital of Valladolid from 1992 to june 2008. Demographic information and tumor features were introduced in Microsoft Access database. Results were analyzed with SPSS (version 15.0). Results Among a total of 314 cases, the mean patient age at diagnosis was 49 years, 43.3% were females and 56.7% males. Regarding the diagnosis, 149 cases (47.6%) were melanocytic, 124 (39.6%) epithelial, 30 (9.6%) soft tissues and 10 cases (3.2%) lymphoid origin. The majority of tumors were benign (63.9%) followed by the precancerous lesions (28.1%). Most of melanocytic lesions were benign (87.9%) and most epithelial were precancerous (64.5%). Conclusion Most frequent conjunctival tumors were melanocytic origin (the majority benign) and epithelial (the majority precancerous). Melanocytic, epithelial and lymphoyd tumors accounted for 90% of cases. These results are similar to others series previously published.
Purpose Pigmented lesions of conjunctiva account for 50% of conjuntival tumors.The purpose of this study was to evaluate the frequency of incidence,clinical characteristics and distribution of these pathologies in a referral oncology unit. Methods Retrospective observational cases series of patients with diagnosis pigmented conjuntival lesions were studied at the Ocular Oncology Unit of Valladolid Clinical Hospital dated from January 1992 until June 2008.Clinical chart of consecutive cases were reviewed through evaluation of the clinical features. Demographic data (age,sex,background) and clinical features (shape,location,ocular and extraocular extension) have been registered in a data base design in AccessXP and statistical SPSS 15 analysis. Results 314 cases were diagnosed with conjuntival tumors, 149 (47%) corresponded to melanocytic tumors; mean age was 42 years, and 52% were females. 73.2% were benign tumors, 22.1% precancerous and 4.7% malign. Comparing clinical characteristics of PAM and melanoma we found significant clinical differences (p<00,5) regarding clinical presentation, 100% melanomas presenting as a growing lesion;limbal involvement was 42.9% for melanoma and 62% for PAM;Corneal involvement was 28.5% for melanoma compared to 17.2% of PAM and 2% of Nevus. All nevus were circumscribe lesions,38% of PAM were diffuse/multicentrics and 42,9% de melanomas were multicentricts;Mean age at diagnosis was 38 years for nevus,53.5 for PAM and 61.3 for melanomas. Conclusion Pigmented lesions were more frequent tumor in our serie.Most of them benign.Clinical characteristics were related with precancerous or malignal lesions were growing onset,multicentric lesion with corneal and limbal involvement and older age.
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