Oral communication abstracts cases respectively. The cervix was measured using three techniques between the external os (EO) and the internal cervical os (IO) (single straight line, two straight lines, tracing), and the same three techniques between the external os and the lower pole of the egg (LPE). All measurements were repeated to assess the intra and inter operator variability. The value of measurements to predict PTB was compared based on ROC curves. Results: Mean cervical length examined by the single-line, two-lines and trace, from the EO to the IO, approaches were 37.4 mm (+/−3.9 mm), 39.1 mm (+/−4.2 mm), and 39.1 mm (+/−4.3 mm) respectively. Mean cervical length examined by the single-line, two-lines and trace, from the EO to the LPE, approaches were 48.7 mm (+/−7.7 mm), 52.7 mm (+/−8.7 mm), and 54 mm (+/−9.2 mm) respectively. The three methods using the OI were the most useful to predict preterm birth before 34 week's gestation. The most discriminating was the tracing techniques (AUC = 0.85) with a cut off of 37 mm (Se = 87%, Sp = 70%). However intra-and inter-operator agreements were higher with LPE-based methods as compared to IO-based methods. Conclusions: Tracing and single line methods from EO to IO have greater potential to predict preterm birth before 37 weeks' gestation although they have lower reproducibility than LPE-based methods. OC07.02 Clinical significance of the presence of amniotic fluid 'sludge' in asymptomatic patients at low and high risk for spontaneous preterm delivery

Virtual poster abstractsrarity and diverse presentation. The aim of this systematic review and meta-analysis was to investigate the perinatal outcomes of fetuses with ICH. Methods: Medline, Embase, Clinicaltrials.gov and Cochrane Library databases were searched. We included studies reporting the outcomes of fetuses with ICH. The primary outcome was perinatal death (PND), i.e. the sum of intra-uterine (IUD) and neonatal death (NND). The secondary outcomes were IUD, NND, TOP, need for surgery/shunting at birth, cerebral palsy, neurodevelopmental delay, and intact survival. Outcomes were explored in the whole population and for intra and extra-axial ICH. Meta-analyses of proportions were used to combine data, we reported pooled proportion and their 95% confidence intervals (CI). Results: 16 studies (193 fetuses) were included. PND occurred in 14.6% (95%CI 7.3-24.0), of fetuses with ICH. Of those liveborn, 27.6% (95%CI 12.5-45.9) required a shunt after birth and 32.0% (95%CI 22.2-42.6) had cerebral palsy. 16.7% of children had mild and 31.1% experienced severe neurodevelopmental delay. A normal outcome was reported in 53.6% fetuses. Looking at location, PND occurred in 13.3% (95%CI 5.7-23.4) of fetuses with intra-axial and in 26.7% ) with extra-axial bleeding. In cases with intra-axial hemorrhage, 24.7% required a shunt after birth and 27.1% had cerebral palsy. Mild and severe neurodevelopmental delay were observed in 15% (95%CI 6.9-25.6) and 32.3% 3) of cases, respectively, while 51.9% experienced a normal outcome. Robust evidence for fetuses with extra-axial hemorrhage could not be extrapolated due to the small number of cases. Conclusions: Fetuses with ICH are at high risk of perinatal morality and impaired neurodevelopmental outcome. Postnatal shunt placement was performed in 28% and cerebral palsy was diagnosed in approximately one third of these infants.