Pathomechanism of lesions in the course of trichinellosis was discussed, representing a sum of immunopathologicaI, pathomorphological and biochemical phenomena. Particular attention was devoted to clinical pathology of the visual organ, which prevails at the acute stage of trichinellosis. In evaluation of clinical signs/symptoms manifested in the visual organ traits of its anatomic, morphological structure, function of the eyeball muscles and eyeball vascular system were taken into account. Ocular lesions in the course of trichinellosis reflect in principle angiomyositis due to immunopathology resulting from migration of Trichinella larvae to many organs and to structures of visual system.

Purpose Rating circadian biorhythms of the eye‐wall tension and cardiovascular system functional parameters in normal subjects(N) and patients with primary open‐angle glaucoma(POAG), normal tension glaucoma(NTG), ocular hypertension(OH). Methods Study population: 50 Ns, 30 POAGs, 10 NTGs and 7 OHs. Simultaneous, 24 hours continuous ocular tonography Triggerfish and ECG/Blood pressure Holter recordings. The comparison in 4 time intervals, set basing on time of falling asleep(F) and awakening(W). Data are compared within intervals (IN) 1:(F‐5hrs,F], 2:(F,F+3], 3:(F+3,W], 4:(W,W+5] Results Similar eye‐wall tension profiles for N and OH were detected, both decreasing in IN4, OH shows higher values in IN3. POAG and NTG tension profiles are different in IN4 with noticeable change for POAG with its value increase in opposite to others. Cardiovascular parameters show the similar characteristics of SAP for all cases with the highest value for OH and the lowest for N. The recordings for DAP show the noticeable difference for NTG, where the profile is changing rapidly between the highest values in INs2 and 4 to the lowest one in IN3. Additionally, only for OH the IN3 value is higher than IN4 one. The comparison of heart rate profile shows a noticeable difference for POAG. All data will be presented Conclusion The study showed specific, group dependent, biorhythms for 24‐hour circadian eye‐wall tension and functional parameters of cardiovascular system. These figures bring new insights into the pathogenesis of glaucomatous neuropathy and indicate the location of potential handle points for individual time‐dependent therapeutic options.

Susac syndrome is an uncommon autoimmune microangiopathy characterized by a combination of encephalopathy, branch retinal artery occlusions (BRAO), and hearing loss. In this report, we present a detailed history of a 31-year-old man with Susac syndrome with thrombophilia. The diagnosis was based on clinical signs and neurological, otolaryngological and ocular examination. Fluorescence retinal angiography showed right BRAO. A slight (30 dB) sensorineural lowering of the hearing level was observed in the audiogram. Numerous ovoid lesions in the corpus callosum were detected in magnetic resonance (MR). The applied treatment included glucocorticosteroids, disease-modifying antirheumatic drugs, anticoagulant treatment and immunoglobulin infusions. After treatment, ophthalmologic symptoms receded, the recanalization of BRAO was detected in angiography, and the lesions in the corpus callosum were reduced in control MR. To date, this is the first report showing the effective treatment of Susac syndrome, which was confirmed simultaneously in MR and fluorescein angiography in a case of Susac syndrome with thrombophilia.