Background Early-Onset Schizophrenia (EOS) is rare but severe mental health disorder in children and adolescents. Diagnosis of schizophrenia before the age of 18 years remains complex and challenging, especially in young children. In France, there are no recent reliable epidemiological data about the prevalence of EOS. The present study evaluates the EOS rate in a target clinical population of children and adolescents in psychiatric and medico-social care centres in the SouthEast of France. Methods Psychiatric and medico-social centres for children and adolescent in the geographical area have been contacted, and after receiving their agreement to participate in the study, eligible patients corresponding to inclusion criteria were selected based on patients' medical records. Main inclusion criteria were age 7 to 17 years and intelligence quotient > 35. EOS categorical diagnosis was assessed by Kiddie-SADS Present and Lifetime psychosis section. Results 37 centres participated and 302 subjects have been included in the study. The main result was the categorical diagnosis of EOS in 27 subjects, corresponding to a rate of 8.9% in the study population. Half of the patients presented mild to moderate intellectual deficiency. Interestingly, only 2.3% had a diagnosis of schizophrenia spectrum disorder noted in their medical records before standardized assessment.

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IntroductionChildhood-onset schizophrenia (COS) is a rare but severe psychiatric disorder with important individual, family and societal consequences. Its prevalence is approximately 2 per 10.000 in the general population and the incidence of COS increases with age.ObjectivesThe main objective of our study was to evaluate the prevalence of COS in French medical-social institutions or psychiatric day hospitals for children and adolescents in the PACA region. The secondary objectives were:to estimate the prevalence of children with both COS and autism diagnosis,to characterize clinical and neurocognitive presentation of COS using the evaluation of intensity of positive and negative symptoms (PANSS, SANS), of thought disorganization (TLC), of cognitive functioning, and of attention and executive functions (verbal fluency, TMT A, TMT B).MethodsSubjects were patients from medical-social and psychiatric care centers for children and adolescents in three PACA sub-regions in the south-east of France. The study included French speaking girls and boys between 7 and 18 years old, registered in a partner structure of the study, and presenting an IQ > 35 (WISC-IV). The study design was constituted by two phases: the first one was the categorical diagnostic phase using the psychosis section of the Kiddie-SADS Present and Lifetime Version. The second phase consisted of the dimensional COS diagnosis and neurocognitive exploration for the subjects fulfilling the DSM-IV diagnostic criteria for schizophrenia.ResultsThe diagnosis of COS was not exceptional in this population. Most subjects diagnosed with COS also presented autism diagnosis and mental retardation.

IntroductionConventional treatment programs of anorexia nervosa are successful in the restoration of body weight; however, recidivism is common and the rate of relapse is high. For twenty years, The Child and Adolescent Psychiatric Department of the University of Nice used to offer a standard treatment based on psychotherapy for both in/out-patients suffering from anorexia nervosa.ObjectiveProgressively, we have developed an innovative pattern of care based on the psychopathologic hypothesis of troubles in early integration of perceptive functions. This way of caring constitute a form of therapy to fight anorectic symptoms by the re-appropriation of feelings and the affective reminders linked to them.MethodsWe have created 4 therapeutic workshops. Three of them use sensorial stimuli: olfactory, tactile-kinesthetic and auditory. The fourth one is a discussion group. We propose all adolescents to try these workshops in addition to the normal care program.ResultsWe note two principal effects of this innovative way of caring: the reduction of the number and the duration of hospitalizations and the improvement of therapeutic alliance.ConclusionThe scientific assessment of the impact of this sensory way of caring on the BMI, on the therapeutic alliance and on the hedonic faculties over 2 years is being. And the results should objectify our clinical findings.The use of sensory pathways and their relationship to memory traces and emotions helps the lifting of denial, the sagging of cleavages and reduces pain following the necessary weight regain in the institutional treatment of adolescent anorexia nervosa.