Aim. To study the influence of socio-psychological factors, factors associated with the disease, the patient, and psychopathological disorders on the treatment compliance.Methods. Structured interviews were conducted with 151 patients (57 patients with irritable bowel syndrome, 57 - gastroesophageal reflux disease, 37 - peptic gastric ulcer and duodenal ulcer). Compliance was assessed using Morisky-Green validated test. Patients were divided into three groups: the first group - compliant patients, the second - risk group, the third group - non-compliant patients.Results.Negative effect on compliance had the following socio-psychological factors: employment, lack of higher education, age from 40 to 49 years, non-constructive model of parent-child relationships, conflict relationships in their own family. Overprotective parenting was mentioned more often in the third group than in the first (20.7 and 42.3%, pConclusion. The influence of certain socio-psychological factors, factors associated with the disease, the patient and the psychopathological disorders presence on the treatment of patients with gastrointestinal diseases was identified, and therefore comprehensive gastroenterologist and psychiatrist monitoring with the subsequent treatment of psychopathological syndromes is necessary.

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