According to the local traditional healers in Ooty, leaves of Passifl ora mollissima Bailey are being used as an antidiabetic drug. In this direction, the ethanol extract of Passifl ora mollissima was tested for its anti diabetic activity in alloxaninduced diabetic rats. The extract was studied at two dose level, 100 mg/kg and 200 mg/kg respectively. The activity was compared with reference standard, phenformin and control. The plant extract at a dose of 100 mg/kg and 200 mg/kg signifi cantly (P<0.001) lowered the blood sugar level of hyperglycemic rats.
Family apiaceae, an important source of bioactive compounds, used for the treatment of many diseases since ages. Objective: Present study was conducted to explore active components of Cuminum Cyminum essential oil. Endeavor of the current study was to investigate the phytochemical contents and antibacterial assessment of essential oil against gram positive and negative bacteria. Method: Essential oil was extracted from seeds by hydrodistillation, dried and stored at -4oC. physical and chemical characterization was done. Antibacterial activity was also determined. Results: GC-MS analysis revealed major components cuminal 35%, γ-terpinene 32%, α-terpinene-al 7%, γ-terpinene 4.45%, daucene 4.3%, and trans-caryophyllene 5.342%, some trace components like myrcene 0.12%, 1-8 cineole, and γ-terpinene-7-al were also present. Conclusion: Chemical components (cuminal, turpentine, daucene, caryophyllene) present in cumin essential oil is responsible for its biological activities.
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