Background: Pancytopenia is one of the important haematological derangements. Thorough investigation for ascertaining the cause is important. Subjects and Methods: The present cross-sectional study was conducted upon 112 patients of pancytopenia. Profile of the patients, clinical features and findings of haematological investigations and bone marrow aspiration were noted. Results: Mean age of the patients was 46.7 ± 9.3 years. Pallor was seen in all the patients. Megaloblastic anemia was present in 36.6%, acute leukemia in 11.6%, hypersplenism and lymphoprofilerative disorder each in 10.7%. Conclusion: Hematological investigations and bone marrow aspiration in patients suffering from pancytopenia is useful.

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