Funding and support: By JACEP Open policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org). The authors have stated that no such relationships exist.

120 received a follow-up prescription (79%). A total of 287 patients received treatment (90%). Follow-up treatment rate was 81.1% for Chlamydia, 78% for gonorrhea, and 53% for dual-infected patients. Disease burden (46%) and undertreatment rate (55.5%) was greatest among adults between 20-29 years. Female patients had a lower empiric treatment rate (44%) compared to males (72%). Conclusion: Overall STI treatment rates from ED-based diagnosis were 90%. The largest opportunities for improvement exist in young adult females with chlamydia between 20 and 29 years.