During World War II, the US government detained over 120,000 Japanese American men, women, and children in internment camps. Two-thirds were American citizens, yet they were treated as enemies of the American people. After the war, historians and activists used archival records created during internment to prove that it had been unjustified by military necessity. They succeeded in overturning Supreme Court rulings and achieved redress for former internees. By relying on the documentary record created during internment and preserved in archives, it was later possible to hold the American government accountable for the violation of people's rights. The very documents that were originally used to control the Japanese American population became the documents that enabled recognition of injustice and led to the conclusion of the redress movement.
Coaggregation between bacterial species is integral to multi-species biofilm development. Difficulties in rapidly and reproducibly identifying and quantifying coaggregation have limited mechanistic studies. This paper demonstrates two complementary quantitative methods to screen for coaggregation. The first approach uses a microplate-based high-throughput approach and the other uses a FlowCam(™) device. The microplate-based approach enables rapid detection of coaggregation between candidate coaggregating pairs of strains simultaneously while controlling for variation between replicates. The FlowCam(™) approach allows for in-depth analysis of the rates of coaggregation and size of aggregates formed.
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