Objective
To measure the impact juvenile localized scleroderma (jLS) has on family quality of life and to identify predictors of family impact in this population which may inform the development of tailored resources to enhance family functioning for patients with jLS.
Methods
A retrospective cohort study of pediatric patients with jLS and their families was conducted. Five questionnaires were administered at each visit: Pediatric Quality of Life Inventory Family Impact Module (PedsQL‐FIM), PedsQL 4.0 Generic Core Scales (PedsQL‐Generic), PedsQL Rheumatology Module (PedsQL‐RM), Child Health Assessment Questionnaire (CHAQ), and Children's Dermatology Life Quality Index (CDLQI). Linear mixed models with random intercepts for each patient were used to find relationships between family impact scores and clinically relevant variables over time. Variables of interest included disease activity status, methotrexate use, jLS distribution, and scores for PedsQL‐Generic and PedsQL‐RM.
Results
The median baseline PedsQL‐FIM total score was 80.9 (IQR = 76.6‐97.4). Adjusting for age and sex, the most significant predictors of family impact were PedsQL‐Generic scores and four of five PedsQL‐RM dimensions (all P < .001); methotrexate use had borderline significance (P = .06). Family impact increased more significantly over time in older patients. In multivariable modeling, PedsQL‐Generic total score and jLS “other” distribution were significant for predicting an increased PedsQL‐FIM score (P = .003 and P = .03, respectively).
Conclusions
JLS has a moderate family impact. Family impact is predicted by patients’ general and disease‐specific health‐related quality of life (HRQL) and their jLS subtype. There is a trend toward increased family impact with methotrexate treatment. This study emphasizes the importance of family‐centered care in jLS.
Ophthalmology residents can complete a full cataract surgery independently after 5.1 ± 3.4 months of continuous surgical training with a low posterior capsular rupture complication rate of 0.7% ± 0.7%.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.