Background: Suxamethonium remains the best option for rapid sequence induction, it is the only depolarizing muscle relaxant in clinical use. However, fasciculation and myalgia are frequent adverse effects of the drug. Myalgia can last for several days with associated discomfort. Non-depolarizing muscle relaxant and magnesium sulphate have been tried as pretreatments to attenuate the fasciculation and myalgia with varying results.Methods: A double blind, randomized study of 100 adult surgical patients of ASA I or II Class were recruited to receive either intravenous atracurium (0.05mg/kg) (Group A) or intravenous magnesium sulphate (30mg/kg)(Group B). The occurrence, severity and duration of fasciculation as well as the occurrence and severity of post-operative myalgia were also recorded.Results: Muscle fasciculation occurred in 39 (78%) patients in Group A and 27(54%) patients in Group B (p= 0.001). The severity of fasciculation was mild to moderate in Group B while Group A in addition also recorded some cases of severe episodes of fasciculation. Mean duration of fasciculation in Group A waslonger (28.48 ± 1.07sec) than in group B (19.44± 1.93seconds) (p= 0.001). Post-operative myalgia was not experienced at 6hrs and 48hrs, while 2 patients (1 in each Group) had it at 12hrs. At 24hrs, postoperative myalgia was present in 13(26%) patients in group A and 5(10%) patients in group B, (p=0.043). The severity of post-operative myalgia recorded both at 12hrs and 24hrs was mild.Conclusion: Magnesium sulphate demonstrated better efficacy at reducing fasciculation and postoperative myalgia than atracurium

Background: Hypertension in diabetes is an added burden and the comorbidity a faster genesis of many cardiovascular diseases that exposes the diabetics to several complications, disabilities and higher mortality rate than the non-diabetics. This study therefore asses the knowledge and control practice of hypertension among the hypertensive diabetics attending the endocrine clinic of LAUTECH Teaching hospital Osogho, Osun state.Methods: A quantitative descriptive survey design was adopted and a total enumeration method was used in recruiting 102 hypertensive diabetics. A structured questionnaire was administered and used to collect data. Descriptive statistics was used to answer the research questions.Results: The overall knowledge level of hypertension among the hypertensive diabetics was above average with overall mean score of 54.01 (65.9%). The control practice level was fair with overall mean score of 45.1%.Conclusions: Efforts to increase the knowledge and control practices of hypertension should not focus only on general health education, but individual specific knowledge needs. practical sections that show case the lifestyle practices that will explain what hypertension self-care maintenance, monitoring and management practices such as exercise sections, diet sections actually means should be incorporated in the clinic routine.