Objective. To assess the structure of thyroid pathology in young elite athletes, depending on sex and type of sports. Materials and methods. The study included data from outpatient records of members of national sports teams, who underwent a comprehensive medical examination. Data of a random sample of 2307 outpatient records of young athletes in 26 sports were analyzed. Results. The prevalence of thyroid pathology in young elite athletes was 22.5%. Thyroid focal changes were detected in young athletes in 13.74% of cases; chronic autoimmune thyroiditis and subclinical hypothyroidism – in 4.2% and 3.85%, respectively. The frequency of single-node non-toxic goiter was 1.21%. Subclinical hypothyroidism was more often detected in combat and speed-power sports, while thyroid focal changes were more common in cyclic sports, team sports and complex-coordination sports. Nodular goiter was most often diagnosed in athletes engaged in cyclic sports. Conclusion. Young elite athletes are characterized by a high frequency of thyroid diseases. The features of the structure of thyroid pathology in certain sports were revealed. Further studies are needed to identify factors contributing to the development of thyroid diseases in young elite athletes. Key words: children, elite sports, endocrine pathology, thyroid diseases.

Introduction. After an infection with the SARS-CoV-2 virus, in some cases, the so-called post-covid syndrome is formed, which includes conditions and symptoms that develop during and / or after the disease, lasting more than 12 weeks, occurring in waves or on a permanent basis, and without a confirmed alternative diagnosis. Vegetative, psycho-emotional disorders, as well as disorders of the cardiovascular system, digestive and some others can be considered as manifestations of the post-covid syndrome. The variety of clinical manifestations of post-COVID syndrome in children can have a significant impact on their quality of life (QoL).Aim. To estimate the quality of life of children aged 5 to 17 years after COVID-19.Materials and methods. The study included 92 children aged 5 to 17 years, divided into two groups. The study group included 62 children (31 boys, 31 girls; mean age 12.0 (7.4; 14.5) years) after a new coronavirus infection. The control group consisted of 30 children who had acute respiratory tract infection of a different etiology and did not have COVID-19 (16 girls and 14 boys; mean age 12.5 (7.5; 15.1) years). The assessment of QoL in children of the study groups was carried out using the Russian version of the PedsQL 4.0 questionnaire. Parental and child forms of the questionnaire were used.Results. The average follow-up period after a coronavirus infection was 6 months (from 3 to 12 months). 92 patient questionnaires were analyzed: 14 in the group of children 5–7 years old, 36 in the group of children 8–12 years old, 42 in the group of children and adolescents 13–17 years old, and 14 parental questionnaires in the group of children 5–7 years old. The indicators of the quality of life of children after COVID-19 were statistically significantly reduced compared to the control group in all age groups. Differences in the assessment of the quality of life by preschool children and their parents were revealed.Conclusions. A significant decrease in the life quality was revealed in children with COVID-19 history after six months (3–12 months) of the disease manifestation in comparison with control group.

Background. Six months after coronavirus disease (COVID-19), more than half of the children have various clinical manifestations of post-covid syndrome. In adult patients without a history of diabetes mellitus, cases of carbohydrate metabolism disorders against the background of COVID-19 and in the long term after the disease have been described. Coronavirus infection in adult patients with lipid disorders is associated with a high risk of severe COVID-19. A 12-year follow-up of patients with severe acute respiratory syndrome (SARS) caused by SARS-CoV showed that they were at an increased risk of developing dyslipidemia. For patients who have undergone SARS-CoV-2, there are no such data due to the short follow-up period. Studies in children evaluating the impact of coronavirus disease on the state of carbohydrate and lipid metabolism are isolated and contradictory. Aim. To compare indicators of carbohydrate and lipid metabolism in children after a coronavirus disease with a control group of healthy peers without a history of COVID-19. Materials and methods. The study included 108 children aged 3 to 17 years, divided into two groups. The study group included 50 children (mean age 12.0 [7.4; 14.5] years) after a coronavirus disease. The average follow-up period after the disease was 6 months (from 3 to 12 months). The control group consisted of 58 healthy peers (mean age 12.5 [7.5; 15.1] years) without a history of COVID-19. All children underwent an assessment of the level of glucose in the blood serum, lipid metabolism and the calculation of the triglyceride-glucose index (TyG index). Results. The frequency of impaired fasting glycemia in children after a coronavirus disease was 2% and was comparable to the control group of healthy peers without a history of COVID-19. The TyG indices in the study groups did not differ significantly (4.46 [4.11; 4.65] vs 4.33 [4.0; 4.47]; p=0.37). None of the children included in the study showed an increase in the TyG index to values corresponding to the criterion of insulin resistance. An assessment of the state of lipid metabolism also did not reveal significant differences in the levels of total cholesterol, LDL, HDL and triglycerides, depending on the presence of a history of coronavirus disease. Conclusion. In children six months (312 months) after coronavirus disease, there was no increase in the frequency of impaired fasting glycemia and insulin resistance compared to healthy peers without a history of COVID-19.