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The designing of square pulse generators using pulseforming lines (PFLs) made up of identical L and C, was reviewed in this study. 14 different types of PFL were analyzed utilizing PSpice simulation results. These PFLs were characterized with respect to their distinct features: the number of forming lines (single or double), the circuit relationship of the PFL and load (parallel or series), the types of energy storage (current source, voltage source or a combination of both). The characteristic impedance, output parameters such as pulse width, voltage and current magnitudes, and power were derived for each scheme. The merits and demerits of the output parameters were also included.

Polybutylcyanoacrylate nanoparticles represent a potential system for delivering medicinal agents. The present report describes development of a method for radiation sterilization of medicinal formulations of doxorubicin based on polybutylcyanoacrylate nanoparticles. The physicochemical properties of the medicinal formulation were studied after gamma irradiation and irradiation with accelerated electrons over the dose range 10 -35 kGy. The chemical structure of doxorubicin and the polymer carrier was found to be intact after irradiation at a dose of 25 kGy. Irradiation at these doses also had no effect on the colloidal properties of polymer nanoparticles, which retained their stability to aggregation and sedimentation. The optimum sterilizing dose was 15 kGy.

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