Aspergillus niger is one of the most important microorganisms used in biotechnology. It has been in use already for many decades to produce extracellular (food) enzymes and citric acid. In fact, citric acid and many A. niger enzymes are considered GRAS by the United States Food and Drug Administration. In addition, A. niger is used for biotransformations and waste treatment. In the last two decades, A. niger has been developed as an important transformation host to over-express food enzymes. Being pre-dated by older names, the name A. niger has been conserved for economical and information retrieval reasons and there is a taxonomical consensus based on molecular data that the only other common species closely related to A. niger in the Aspergillus series Nigri is A. tubingensis. A. niger, like other filamentous fungi, should be treated carefully to avoid the formation of spore dust. However, compared with other filamentous fungi, it does not stand out as a particular problem concerning allergy or mycopathology. A few medical cases, e.g. lung infections, have been reported, but always in severely immunocompromised patients. In tropical areas, ear infections (otomycosis) do occur due to A. niger invasion of the outer ear canal but this may be caused by mechanical damage of the skin barrier. A. niger strains produce a series of secondary metabolites, but it is only ochratoxin A that can be regarded as a mycotoxin in the strict sense of the word. Only 3-10% of the strains examined for ochratoxin A production have tested positive under favourable conditions. New and unknown isolates should be checked for ochratoxin A production before they are developed as production organisms. It is concluded, with these restrictions, that A. niger is a safe production organism.

Using a participatory action research approach, community-based older adult service providers and university researchers partnered to explore older adult care transitions through the health care system, specifically from a hospital stay to home with rehabilitative services. Qualitative findings of transitioning home from both older adult and service provider perspective included three major themes: social support, communication, and adjusting to home and planning for the community. In addition, resources developed through the project are discussed with implications to practice. shared their experience and insights regarding care transitions. We also wish to acknowledge the important work of graduate students involved carrying out this project:

For almost a decade the research literature has reflected both the scarcity of new knowledge regarding alcohol use or abuse among the elderly and the need to address the problem. Current theoretical perspectives on probable trends of alcohol-related problems among older persons include historical-cohort prediction, biological and clinical geriatric expectations, and sociocultural-economic expectations. These theoretical perspectives are frequently in opposition to each other and are largely untested with appropriate data. This paper introduces the principal theoretical perspectives of alcohol use among the elderly and presents recent data from a probability sample of noninstitutionalized elderly persons regarding alcohol consumption patterns, abstinence, and the influence of increasing chronological age and economic security on alcohol consumption.

Band 12, Heft 2 1969 WOHLLEBEN und SCHUSTER, Aktivierungsanalyse mit Deuteronen 75 method. (iii) The procedure is simple. The time required for the chemical procedure is about 20 min excluding cooling and equilibration steps. The method seems suitable for the routine and many sample analysis of uranium of the amount higher than 0.1 flg.

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