Objective: to determine the effect of increasing rates of Mocap® 6EC (ethoprophos-AMVAC) on grape (Vitis vinifera) own-rooted cv. Flame and cv Red Globe grafted onto Quebranta rootstock Meloidogyne spp. control. Methodology and Results: two field experiments of increasing rates of 0, 6, 8, 10, and 12 L ha-1 of Mocap® 6EC (ethoprophos-AMVAC) using a complete randomized block design with 4 replicates were set up on grape (Vitis vinifera) own-rooted cv. Flame and cv Red Globe grafted onto Quebranta rootstock for Meloidogyne spp. control. To quantify nematode numbers in soil and roots, and the number of galls in a linear meter root, soil and root samples were taken just before treatment and at 30, 60 and 90 days after product application. In both experiments, at 30, 60 and 90 days after the application, a decreasing linear effect on Meloidogyne spp. numbers in soil (P< 0.0001) and roots (P≤ 0.0002) and number of galls (P< 0.0001) was observed as rate increased. The average reduction was of 4.6, 4.9 and 5.2; and 5.5, 6.0 and 6.3 individuals per 100 g of soil, and 5.6, 9.9 and 9.9, and 4.9, 7.7 and 8.2 nematodes per 100 g of roots, and 2.0, 4.0 and 4.3, and 1.8, 3.9 and 4.9 galls per linear meter of root, by every litre of increase on the applied rate, at 30, 60 and 90 days post application, for the experiment at Ica and Lima department, respectively. Differences in biological efficacy among rates were found for soil (P< 0.0001) and root (P< 0.0001) nematode control, and number of root galls (P< 0.0001), increasing the control as the rate increased in both experiments. Efficacy in soil nematode control varied from 51 to 98% and 73 to 99%, in roots it varied from 61 to 85% and 61 to 87%, and in the number of root galls from 55 to 84%, and 58 to 81% for the experiment at Ica and Lima department, respectively. Conclusions and application of findings: All Mocap® 6EC rates tested reduced Meloidogyne spp. in soil and roots, and the number of galls per linear meter of root, with higher reductions as the rate increased. Then the recommended rate is 10-12 L ha-1 incorporated in a drip irrigation of two hours.