Цель исследования: изучение СAT-теста у больных хронической обструктивной болезнью легких (ХОБЛ)� Материалы и методы. Обследовано 53 больн ых ХОБЛ� Исследуемую группу составляли больные ХОБЛ, имеющие длительный стаж куре-ния� Исследование функции внешнего дыхания проводили на многомодульной установке типа MasterLab/Jaeger� Пациентам предлагалось заполнить опросник Бека для выявления депрессии� Для оценки самочувствия использовали CAT-тест� Результаты. По мере прогрессирования стадии ХОБЛ отмечено возрастание количества баллов CAT: у больных ХОБЛ 2-й стадии CAT
Background and Aims: Spirometry is noninvasive test for diagnosis , assessment airflow limitation and to plan management in COPD. GOLD guideline recommended to evaluate staging in airflow obstruction by post-bronchodilator FEV 1 level before treatment. FEV 1 may be correlated with dyspnea symptoms and health status but takes time to evaluate for outpatient visit .The 6-minute walk test (6MWT) is a practical simple test that requires no expensive equipment or advanced training technicians and correlates better to measure functional capacity .This study was aimed to determine correlation and efficacy between FEV 1 and 6MWD on dyspnea symptoms and functional status in COPD patients. Methods: Retrospective study conducted of 493 diagnostic COPD patients who attending outpatient department between 2014 to 2016 .All patients underwent spirometric measurement post-bronchodilator FEV 1. 6MWT was performed following American Thoracic Society (ATS) which distance was recorded in meters.Baseline characteristics ,Modified British Medical Research Council (mMRC) Questionnaire and COPD Assessment Test (CAT) were recorded and calculated .Correlation coefficient (r) analysis by Spearman rank correlation. Results: This study showed significantly linear correlation of FEV 1 (L/-min) with 6MWD(r = 0.33, P < 0.001), mMRC(r = 0.33, P < 0.001), and CAT (r = 0.22 P =0.001),otherwise there was inverse linear correlation significantly between 6MWD with mMRC(r=-0.29,P < 0.001) and CAT(r=-0.24,P < 0.001). Conclusions: 6MWD can be useful for evaluation and follow-up stable COPD patients effectively when the facility of spirometry is limited.
ФГБОУ вО «Петрозаводский государственный университет», г. Петрозаводск, Россия Цель исследования: изучение индекса коморбидности Charlson у больных хронической обструктивной болезнью легких (ХОБЛ). Материалы и методы. Обследовано 207 больных ХОБЛ, имеющих длительный стаж курения (индекс курильщика 240 и стаж курения 40 пачек/лет). Для расчета суммарного сердечно-сосудистого риска использовали шкалу SCORE. Исследование функции внешнего дыхания проводили на многомодульной установке типа «MasterLab/Jaeger». При оценке коморбидности применяли индекс Charlson. Результаты. В исследуемой группе индекс коморбидности Charlson составил 4,49 ± 1,50 балла, лица с очень высоким суммарным сердеч но-сосудистым риском составили 68,9%. Установлена достоверная корреляционная связь между суммарным сердечно-сосудистым риском и индексом коморбидности Charlson. Выявлена прямая связь средней силы между индексом коморбидности и показателем пачек/лет. Уста новлены достоверные корреляционные связи между индексом коморбидности и ЖЕЛ (r =-0,39, p < 0,005), между индексом коморбидности и RV (r = 0,46, p < 0,05).
The purpose of this study was to assess the severity of depression in patients with chronic obstructive pulmonary disease (COPD) with hypertensive disease. Research methods: patients with COPD in combination with hypertensive disease (n = 41) were studied. The study group consisted of patients with COPD with a long history of smoking. The study group was dominated by men (78.05%). The av-erage age of the patients was 64.51 ± 8.66 years. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Exercise tolerance (6MWD, m), degree of dyspnea (MRC scale) were studied. The CAT test (COPD Assessment Test) was used to assess the state of health. Patients were asked to complete a Beck Depression Inventory. Results: Patients with grade 2 COPD accounted for 43.9%, with grade 3 COPD - 39.02%, with grade 4 COPD - 17.08%. Severe depression was diagnosed in 16.67% of patients with grade 2 COPD, in 37.50% of patients with grade 3 COPD and in 42.86% of patients with grade 4 COPD. Very Severe depression was noted in 28.57% of patients with grade 4 COPD. In 50% of patients with severe and very severe depression, a serious effect of COPD on the quality of life (21– 30 CAT points) was re-vealed, a very serious effect of COPD on the quality of life (31– 40 CAT points) was noted in 35.71% of patients. In general, in the group of COPD patients with essential hypertension, severe depression according to the Beck scale was found in 29.27%. Very severe depression was noted in 4.88% of pa-tients with COPD with essential hypertension.
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