To report a single-center experience of the technical success and clinical 90-day outcomes of MT for anterior circulation ELVOs performed by interventional radiologists. Materials: A retrospective review identified 178 consecutive patients from January 2016 to March 2018 who underwent MT for anterior circulation ELVOs within 6 hours of symptom onset and initial NCCT ASPECTS 6, or presenting >6 hours but further selected with CT perfusion. Eight interventional radiologists performed the procedures. Technical and clinical outcomes were compared to the HERMES dataset. Results: Eight patients were excluded for spontaneous revascularization. The average age was 66 years versus 68 years for HER-MES. The average NIHSS was 17 for both groups. Vessel occlusions included: M1 59% (100/170) versus 69% (439/633), M2 12% (20/ 170) versus 8.0% (51/633), ICA 29% (50/170) versus 21% (133/ 633), and tandem ICA origin/M1 17% (29/170) (not reported in all trials), respectively. The overall mTICI 2b/3 reperfusion rate was 87% (148/170) versus 72% (405/633), respectively (p<0.05). The mRS 90-day outcome 0-2 rate was 40% (68/170) versus 46% (223/ 645), respectively (p¼0.14). Major procedural complications were 3.5% (6/171) including 2 ICA dissections, 1 M2 MCA air embolization, 1 MCA wire perforation, 1 femoral hematoma requiring transfusion, and 1 anaphylaxis. Symptomatic intracranial hemorrhage rate was 4.1% (7/171) versus 4.4% (28/633), respectively. Conclusions: This single-center experience describes similar technical success and 90-day outcomes for MT of anterior ELVOs by interventional radiologists to the HERMES data set.