Aim: To evaluate the analgesic effect of superior hypogastric plexus (SHP) area infiltration with 20 ml bupivacaine0.5% on post total abdominal hysterectomy (TAH) pain. Patients and Methods: This a prospective randomized, double blind, placebo controlled study, conducted at Benha University Hospital, including sixty women undergoin TAH, thirty women received 20 ml bupivacaine 0.5% and thirty women received 20 ml saline infiltrated in SHP area at end of TAH. Main outcomes measures were total cumulative Nalbuphine consumption and post TAH pain using visual analogue scale (VAS), as well as nausea, vomiting, other analgesic requirements, time spent in post anaesthesia care unit (PACU), time to get out of bed.