In patients with SCF, thrombolysis in myocardial infarction frame counts and hs-CRP are correlated with increased insulin resistance and thus, it can be suggested that insulin resistance and inflammation may, in part, have a role in the pathogenesis of SCF.

Anti-glomerular basement membrane (GBM)

The etiology of posttransplant erythrocytosis (PTE) remains unclear, and the most frequently suggested causative factors are still a matter of controversy. We aimed to investigate serum-soluble stem cell factor (sSCF) along with serum erythropoietin (EPO) levels in renal transplant recipients (RTRs) with PTE. Thirteen RTRs with PTE, 42 RTRs without PTE, and 42 healthy controls were included. Serum sSCF and EPO levels were determined using an enzyme-linked immunosorbent assay kit. Expected and observed/expected EPO levels were calculated. Serum sSCF levels and observed/expected EPO were significantly higher in RTRs with PTE than both RTRs without PTE and controls. In RTRs with PTE, sSCF level was significantly correlated with hematocrit and observed/expected EPO, respectively. Significant correlation was also observed between hematocrit level and observed/expected EPO in RTRs with PTE. Increased sSCF level and inadequate suppression of EPO production seem to have a role in the pathogenesis of PTE.

234etanol, odunun distilasyonu ile elde edilen, kimya endüstrisinde sıklıkla kullanılan, çözücü özelliği taşıyan, renksiz, kokusuz ve acı bir alkol çeşididir. Çeşitli solventler, boya-leke çıkarıcılar, antifirizler, araba camı yıkama sıvıları, kolonya ve ispirto metanol içeren sıvılar-dır. Metanolün kendisi toksik değilse de metabolitleri toksiktir. Alkol dehidrojenaz tarafından formaldehite ve takiben formik aside metabolize edilir. Bu metabolitler metabolik asidoz, körlük, kardiovasküler instabilite, böbrek yetmezliği ve ölüme neden olabilen metanol toksitesinden sorumludur. İntoksikasyon sıklıkla kaza ya da intihar amaçlı oral alımdan sonra olur.1 Ancak oldukça nadiren, inhalasyon, plasental ya da cilt yoluyla dolaCilt Yoluyla Gelişen Fatal Metanol Zehirlenmesi: Olgu Sunumu ve Literatür Derlemesi Ö ÖZ ZE ET T Me ta nol, renk siz, ber rak, ko ku su ve ta dı eta no le ben ze yen, çö zü cü ve te miz lik mad de si birçok kim ya sa lın üre ti min de kul la nı lan ol duk ça tok sik bir mo le kül dür. Cid di me ta nol ze hir len me si, bu mad de le rin in ti har gi ri şi mi ve ya ka za ra çö zü cü le rin oral yol dan alın ma sı ile ge liş mek te dir. Transder mal yol la ge li şen me ta nol ze hir len me si ol duk ça az sa yı da has ta da ra por edil miş tir. Me ta nol zehir len me si nin be lir ti le ri gör me bo zuk lu ğu, be yin öde mi, so lu num yet mez li ği ne ne den olan san tral si nir sis te mi dep res yo nu ve cid di me ta bo lik asi doz dur. Bu ra por da, bi lin cin de bo zul ma, de rin ve hız lı so lu num tab lo suy la acil ser vi se ge ti ri len, cilt yo luy la ge li şen ve fa tal sey re den me ta nol in toksi kas yo nu sap ta nan 57 ya şın da bir ba yan has ta su nul muş tur. Ay nı za man da me ta nol ze hir len me siyle il gi li li te ra tür ge niş bir şekil de göz den ge çi ril miş tir.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Beyin ödemi; asidoz; böbrek diyalizi; zehirlenme A AB BS S T TR RA AC CT T Methanol is an extremely toxic molecule. It is clear, colorless, odorless and has a taste similar to ethanol, and utilized to produce a number of cleaning substances and chemicals. Serious methanol intoxication developeds either with accidental ingestion or after suicidal attemps. Transdermal methanol intoxication has been reported only in a few patients. The signs of methanol intoxications are visual impairment, brain edema, central nervous system depression leading to respiratory insufficiency and severe metabolic acidosis. A 57-year-old female patient admitted to emergency room with impaired consciousness, tachypnea and deep breathing was presented in this report. In addition, the literature on methanol intoxication was reviewed.

Objectives Coronavirus disease 2019 has caused a major epidemic worldwide, and lockdowns became necessary in all countries to prevent its spread. This study aimed to evaluate the effects of staying-at-home practices on the metabolic control of children and adolescents with type 1 diabetes during the pandemic period. Materials and Methods Eighty-nine patients younger than 18 years old who were diagnosed with type 1 diabetes at least one year before the declaration of the pandemic were included in the study. The last visit data of the patients before and after the declaration of the pandemic, and the frequency of presentation of diabetes-related emergencies from one year after diagnosis of type 1 diabetes to the declaration of the pandemic, and from the declaration of the pandemic to the last visit after the pandemic declaration were compared. Results The total number of patients was 89, and 48 (53.9%) were boys. The mean (± standard deviation [SD]) age at diagnosis was 8.4 ± 3.7 years (boys 7.9 ± 3.6 years; girls 8.9 ± 3.9 years). There was no statistically significant difference when the SD values of the anthropometric measurements, and the glycosylated hemoglobin (HbA1c) and lipid profile tests were compared. However, the frequency of admission to the emergency service related to diabetes was significantly different. Conclusions Although the pandemic did not significantly affect the metabolic and glycemic controls of the children with type 1 diabetes included in this study, an increase in the frequency of diabetes-related emergency admissions was noted.