A Prospect to develop Chlorella industry has been conducted since 2015 to 2018. The pure chemical and waste water from oil palm industry as culture media of Chlorella sp. were used in this study. Result of this study indicated that pure chemical and palm oil waste water can promote the growth and product of Chlorella sp. The best growth of Chlorella sp. was found at pure chemical with cell density reached 1.6 x 107 cells/ml and biomass reached 1.24 g/l. The high growth of Chlorella sp. in palm oil wastewater was found at concentration of 20 % with cell desity of 6.6 x 106 cells/ml and biomass reached about 0.36 g/l. The concentration of nitrate in pure chemical culture medium was decreased from 15.43 to 1.46 and in palm oil wastewater was decreased from 13.8 mg/l at the beginning to 2.4 mg/l at the end and phosphate was decreased from 45.822. mg/l to 4.98 mg/l at the beginning to 0.17 mg/l at the end of 14 days culture period. Chlorella powder that was produced in pure chemical medium in this study can be used as Chlorella powder in capsule for human being and from palm oil wastewater medium can be used as supplement food for animal husbandry (calves) in Riau Province.