The range of applicability of superiorization to constrained optimization problems is very large. Its major utility is in the automatic nature of producing a superiorization algorithm from an algorithm aimed at only constraints-compatibility; while nonheuristic (exact) approaches need to be redesigned for a new optimization criterion. Thus superiorization provides a quick route to algorithms for the practical solution of constrained optimization problems.

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In electron tomography the reconstructed density function is typically corrupted by noise and artifacts. Under those conditions, separating the meaningful regions of the reconstructed density function is not trivial. Despite development efforts that specifically target electron tomography manual segmentation continues to be the preferred method. Based on previous good experiences using a segmentation based on fuzzy logic principles (fuzzy segmentation) where the reconstructed density functions also have low signal-to-noise ratio, we applied it to electron tomographic reconstructions. We demonstrate the usefulness of the fuzzy segmentation algorithm evaluating it within the limits of segmenting electron tomograms of selectively stained, plastic embedded spiny dendrites. The results produced by the fuzzy segmentation algorithm within the framework presented are encouraging.

Much recent activity is aimed at reconstructing images from a few projections. Images in any application area are not random samples of all possible images, but have some common attributes. If these attributes are reflected in the smallness of an objective function, then the aim of satisfying the projections can be complemented with the aim of having a small objective value. One widely investigated objective function is total variation (TV), it leads to quite good reconstructions from a few mathematically ideal projections. However, when applied to measured projections that only approximate the mathematical ideal, TV-based reconstructions from a few projections may fail to recover important features in the original images. It has been suggested that this may be due to TV not being the appropriate objective function and that one should use the ℓ1-norm of the Haar transform instead. The investigation reported in this paper contradicts this. In experiments simulating computerized tomography (CT) data collection of the head, reconstructions whose Haar transform has a small ℓ1-norm are not more efficacious than reconstructions that have a small TV value. The search for an objective function that provides diagnostically efficacious reconstructions from a few CT projections remains open.

To reduce the x-ray dose in computerized tomography (CT), many constrained optimization approaches have been proposed aiming at minimizing a regularizing function that measures a lack of consistency with some prior knowledge about the object that is being imaged, subject to a (predetermined) level of consistency with the detected attenuation of x-rays. One commonly investigated regularizing function is total variation (TV), while other publications advocate the use of some type of multiscale geometric transform in the definition of the regularizing function, a particular recent choice for this is the shearlet transform. Proponents of the shearlet transform in the regularizing function claim that the reconstructions so obtained are better than those produced using TV for texture preservation (but may be worse for noise reduction). In this paper we report results related to this claim. In our reported experiments using simulated CT data collection of the head, reconstructions whose shearlet transform has a small ℓ 1 -norm are not more efficacious than reconstructions that have a small TV value. Our experiments for making such comparisons use the recently-developed superiorization methodology for both regularizing functions. Superiorization is an automated procedure for turning an iterative algorithm for producing images that satisfy a primary criterion (such as consistency with the observed measurements) into its superiorized version that will produce results that, according to the primary criterion are as good as those produced by the original algorithm, but in addition are superior to them according to a secondary (regularizing) criterion. The method presented for superiorization involving the ℓ 1 -norm of the shearlet transform is novel and is quite general: It can be used for any regularizing function that is Inverse Problems Inverse Problems 33 (2017) 044011 (24pp)