Sympathoadrenal activity was appraised in ten heat-acclimatized men over a 10-week period, beginning in late summer and ending in autumn. Two overnight urine samples per subject per week were analyzed for norepinephrine, epinephrine, creatinine, and urea. Evidence of relatively high sympathoadrenal activity was obtained in late summer, since a progressive decline appeared in autumn. The catecholamines were shown to relate either to weekly mean maximum temperature or to weekly mean solar radiation. Catecholamine excretion also tended to vary inversely with urea excretion. epinephrine excretion; norepinephrine excretion; heat acclimatization; sympathoadrenal activity in hot climate Submitted on February 25, 1963

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