La distrofia muscular de Duchenne (DMD) es la miopatía más común en niños, de herencia recesiva ligada al cromosoma X y causada por mutaciones en el gen DMD (Xp21.2). Se caracteriza por atrofia y debilidad muscular progresiva, con consecuentes complicaciones musculoesqueléticas, respiratorias y cardíacas, entre otras. Considerando la alta prevalenciade esta condición (prevalencia mundial 0.5 por cada 10 000 hombres) (1,2) y la importancia del manejo multidisciplinar para el diagnóstico oportuno y el manejo adecuado de los pacientes, se realiza un consenso interdisciplinario de expertos para proponer recomendaciones para el diagnóstico y seguimiento de los pacientes colombianos con DMD

No abstract

index (BMI) was measured as an indicator of obesity and the risk was classified according to international benchmarks. We compared the cardiorespiratory fitness by 6-min walk test (6'WT), oxygen consumption by VO( 2 )max, distance and the number of steps such as indicators of fitness. Results: We performed a cross-sectional descriptive study in 40 patients with HF (age 66.8 AE 11.4 years, BMI 27.4 AE 4.8 kg$m -1 , LVEF 40.5 AE 8.3%). In subjects with BMI â&U 26 kg$m -1 negative correlations were observed in the distance by 6'WT (rho Spearman ¼ -0.50), number of steps (rho Spearman ¼ -0.45), VO( 2 )max (rho ¼ -0.49) and LVEF (rho ¼ -0.32). Conclusion: This study suggests that "obesity paradox" is not related to a higher standard cardiopulmonary by VO( 2 )max.

No abstract